Study of blood pressure patterns versus serum lipid parameters in obese human subjects

A study was conducted to determine relationship of obesity with the blood pressure patterns and lipid parameters in preview of its unique local diet patterns. A total of 200 non-diabetic human subjects of either sex were included in the study. They were categorized on the basis of body mass index [BMI] as obese and non-obese. Each group was further divided into 2 subgroups; hypertensive and normotensive. Fasting lipid profile [total cholesterol, LDL-and HDL-Cholesterols and total triglycerides] in each group was determined to compare the levels among various groups. BMI was calculated from height and weight, while blood pressure was measured with a sphygmomanometer. Lipid profile was determined with Merck kits. Diet and related information was also collected from the patients directly. Means of all parameters, except LDL-C, were higher in females than males; among these BMI and HDL-C showed significant difference. There was a significant negative correlation of diastolic blood pressure with HDL-C in obese subjects; all the other parameters were non-significantly correlated. In the non-obese subjects, there was a significant positive correlation between systolic [SBP] and diastolic [DBP] blood pressures and LDL-C. All other parameters were found non-significantly correlated. The analysis of variance was done in four groups namely, obese non-hypertensives, obese hypertensives, non obese non-hypertensives and non obese hypertensives. BMI, SBP, DBP, LDL-C and total cholesterol had significantly different means in the above four groups, while HDL-C and total triglycerides were statistically non-significant [p>0.05] among four groups

Levels of serum Cu, Fe and Zn along with serum total proteins and fractions in disease malnourished children of 4 - 12 years of age

This study was conducted to uncover the differences in the serum Cu, Fe, Zn and proteins in children of different degrees of malnutrition. For this purpose 85 malnourished and 15 normal children of school age [4-12 years] were chosen. Results revealed that serum Fe and Cu were significantly or relatively higher in malnourished than apparently healthy children irrespective of age, sex, socio-economic status or area of living. The levels of serum Zn, however, showed statistically non-significant differences between malnourished and apparently healthy children. Serum levels of total proteins and globulins were significantly or relatively lower in malnourished compared to the children of control group irrespective of age, sex, socio-economic status and area of living. The results of albumin were variable in these groups. While serum total proteins and globulins in male malnourished children were significantly lower compared to the male children of the control group, it was non-significantly different among females. The means of serum Cu, Zn and Fe in severely malnourished males and females were 48.61, 80.40; 50.00, 48.20; 227.15, 229.40 micro g/dL, respectively. These parameters in children of low and middle socio-economic status were 58.30, 90.00; 47.80, 58.67; 240.15, 148.00 micro g/dL, respectively while in severely malnourished children of three age groups [4-6, 7-9 and 10-12 years] were 38.25, 81.00, 71.55; 50.50, 46.66, 49.77; 224.88, 155.00, 279.78 micro g/dL, respectively. It can be concluded from the present study that serum Cu and Fe levels are increased, while serum total proteins and globulins are decreased in children of 4-12 years of age suffering from disease malnutrition

study on iron deficiency anemia and hematological differences around delivery in women of different socio - economic and age groups

This study was conducted on pregnant women admitted to various hospitals of Faisalabad for delivery. They were randomly divided into 3 socio-economic groups [low, middle and high] and each group was further subdivided into 3 age groups of < 25, 26 33 years of patients. The study revealed an overall higher [p<0.05] birth weight of newborn of those born to women of middle socio-economic groups than low and high. Overall mean RBC [106/

Blood glucose; response to two local varieties of apple [pyrus malus, linn] in normal and diabetic human subjects

glycaemic indeces of two local varieties of apple have been determined in normal and diabetic subjects in order to assess their capability to raise blood glucose levels. SUBJECTS: Seven normals and seven diabetics were included in this study to compare their blood glucose responses in both the groups. A glucose tolerance test was performed on each individual for comparison using 50 g of glucose and the amount of each apple variety containing 50 g soluble carbohydrates. METHODS: The serum glucose levels were determined by the glucose oxidase method by using a kit. DESIGN: A controlled clinical trial design was used. The mean glycaemic indices of apple variety I and II were 32.2% and 36.2% in comparison to glucose in diabetic subjects. The mean +/- SEM, area under curve for 50 g glucose was 5209.28 +/- 1789.69 [mg min/dl], for apple variety I was 1174.28 +/- 904.39 [mg min/dl] and for apple variety II it was 2048.57 +/- 894.60 [mg min/dl]. These values for both varieties of apple, are highly significantly [P<0.001] lower than that of glucose. These data have suggested that inspite of high carbohydrate contents present in both varieties of apple tested, they are suitable for the use to diabetics as their dietary fibre contents decrease the blood glucose levels from rising to the abnormally high limits