ABSTRACT
To determine the effect of hyperglycemia on thickness of crystalline lens of eye in diabetic population and its comparison with non-diabetics of same age group. Cross sectional observational study. The study was conducted at Railway General Hospital, Rawalpindi. A total 112 patients over a period of six months were included in study. Ocular lens thickness was measured in 56 diabetic patients and 56 non-diabetic controls by using A-scan biometry. Parameters like duration of diabetes and type of medication were recorded. 112 patients were divided into two groups. In diabetic group [56 patients], most of the patients i.e. [42%] had BSR more than 200 mg/dl. Out of 56 controls, most of the subjects i.e. 54%] had BSR between 70-90mg/dl. Thickness of crystalline lens was in the range of 4.00-6.21 mm with mean of 5.10mm in diabetics and in range of 4.00-4.50mm with mean of 4.16mm in non-diabetic controls. Thickness of crystalline lens was increased in patients who had diabetes for at least 10 years as compared to normal controls