ABSTRACT
Obective: We compared the efficacy of gated blood pool [GBP] ventriculography with echocardiography and contrast ventriculography for measurement of left ventricular ejection fraction [LVEF] in patients with myocardial infarction. Gated blood pool ventriculography [invivo technique] and echocardiography were performed in 30 patients at least after 24 hours but within 48 hours of contrast ventriculography. Echocardiographic methods included: [1] Subjective [visual] estimation of LVEF from 2 dimensional [2D] echocardiography. [2] 2D directed M-mode [Cubed method] echocardiography. Single plane cine ventriculographic ejection fractions were calculated using Dot calibration method. The comparison of GBP ventriculographic LVEF with contrast ventriculographic LVEF and 2D echo estimated LVEF revealed no significant difference in their mean ejection fraction [44.04 +/- 11.93 vs 48.46 +/- 12.78% p = NS] and [44.04 +/- 11.93 vs 47.38 +/- 13.06%, p= NS] respectively, while comparison of GBP LVEF with 2D directed M-mode [cubed method] echocardiography revealed highly significant difference in their mean EF [44.04 +/- 11.93 vs 61.7 +/- 15.65%, p < 0.01]. GBP LVEF has statistically significant correlation with contrast ventriculographic [r = 0.86] and 2D echo estimated [r = 0.77] LVEF, while has poor correlation [r = 0.57] with cubed formula from 2D echo. GBP ventriculography can be utilized accurately for determination of ejection fraction in post myocardial infarction patients for diagnostic and prognostic evaluation
Subject(s)
Humans , Male , Female , Myocardial Infarction , Gated Blood-Pool Imaging , EchocardiographyABSTRACT
To compare the efficacy of gated blood pool versus contrast ventriculography [Gold standard] for determination of ejection fraction in post myocardial infarction patients. Patients and Gated blood pool imaging [BPI] was performed by gated blood pool radionuclide ventriculography or MUGA in 30 patients within 48 hours after single plane [RAO-30] contrast ventriculography. Statistical analysis was done by student "t-test" [unpaired] and by Pearson's correlation co-efficient. Result: There was no significance difference in their mean ejection fraction [44.04 +/- 11.93 Vs 48.46 ' 12.78%, P = NS] and has statistically significant correlation [r=0.86, P=0.171] GBP ventriculography can therefore be utilized accurately for determination of ejection fraction for prognostic and diagnostic evaluation of post myocardial infarction patients
Subject(s)
Humans , Male , Female , Myocardial Infarction , Gated Blood-Pool Imaging , Coronary AngiographyABSTRACT
Hyperglycaemia is often associated with acute myocardial infarction. We observed anecdotally that routine dextrose-water infusion plays some part in raising the blood glucose level during initial treatment in non-diabetic patients with infarction. We tested our observation in a group of 14 patients. In 5 out of 14 patients, IV. line was maintained with heparin lock and in remaining 9, I.V. line was maintained with dextrose-water drip. Blood glucose level was estimated before and after I.V. line maintenance and then daily for 2 days and then on alternate days. It was observed that those patients who were not given dextrose infusion did not show any significant rise in blood glucose level, while 60% of those who were on I.V. dextrose infusion showed some rise in blood glucose level while I.V. line was maintained, and later when I.V. line was discontinued after 24-48 hrs, the blood glucose level fell down to within normal limits. These findings suggest that initial hyperglycaemia in non-diabetic patients may be due to I.V. dextrose infusion