1.
Indian J Dermatol Venereol Leprol
;
2009 Sept-Oct; 75(5): 503-505
Article
in English
| IMSEAR
| ID: sea-140424
ABSTRACT
The metastasis of a visceral malignancy to the umbilicus is known as "Sister Mary Joseph's nodule". It is a rare clinical sign indicating advanced, metastasizing intraabdominal cancer. We report a 50-year-old man who developed metastatic skin cancer in the form of semicircular indurated plaque on top of which was a firm mobile rounded nodule at the umbilical area. Histopathological examination demonstrated diastase-resistant periodic acid-Schiff and mucicarmine positive signet ring cells, suggesting gastric carcinoma. Immunohistochemical staining showed that these cells were positive for cytokeratins and epithelial membrane antigen, suggesting epithelial origin.
2.
Indian J Dermatol Venereol Leprol
;
2009 Jan-Feb; 75(1): 101
Article
in English
| IMSEAR
| ID: sea-53023