vivo effects of some hose spices extracts on the toxoplasma gondii tachyzoites

Toxoplasmosis drugs have the longest history and are still the first choice for most conditions. Alternative drugs such as Co-trimoxazole and Tetracycline have been tried and acclaimed successful. The lack of general acceptance, however, is an indication that the results are not very convincing. A wide range of antibiotics is urgently needed for patients with drug reaction or resistance problems. The anti-toxoplasmic activity of water and ethanol extracts as well as the oil of some hoe spices [Piper nigrum, Capsicum frutescens, Cinnamomum cassia and Curcuma longa], were evaluated in murine models of intraperitoneal infection using the RH strain of Toxoplasma gondii. Female mice were infected with 2x10[2] tachyzoites/ml, and then treated intraperitoneally with the home spices at 100 and 200 mg/kg/day for seven days. The tested extracts reduced the mean number of tachyzoites present in the peritoneal fluid of the experimental mice. The most effective extract was Curcuma longa ethanol extract which showed a 98.6% and 99.2% inhibition of the growth of Toxoplasma tachyzoites in 100 and 200 doses respectively compared to the control infected untreated mice

Two methods for attenuating toxoplasma gondii tachyzoites Rh strain by using ethanol extract of curcuma longa

The ethanol extract of Curcuma longa proved to be an attenuated agent against Toxoplasma gondii [RH strain] tachyzoites in the mice peritoneal fluid by two incubation methods. Groups of female mice were injected by attenuated tachyzoites as 200 tachyzoites / ml, which treated with the ethanol extract of Curcuma longa was previously treated. The result was observed after one week, as no tachyzoites were found in the peritoneal fluid of the experimental infected mice

Recent diagnostic study for the flagellate protozoan trichomonas vaginalis

The signs and symptoms of trichomonasis vaginalis are not adequately sensitive or specific for diagnosis as up to 50% being asymptomatic. Parasitologic diagnosis was usually a must. Diagnosis of trichomonasis was traditionally based on demonstration of the parasite in the normal saline wet mounts of vaginal swaps. In this study, 15/167 married women had T. vaginalis. Wet mount preparation showed 38.5% sensitivity, 98.7% specificity, 71.4% positive predictive value and 95% negative predictive value. InPouch TV culture showed 86.7% sensitivity, 100% specificity, 100% positive predictive value and 98.7% negative predictive value. The results were discussed

Trichomoniasis among women with vaginal discharge in Jeddah city, Saudi Arabia

During the year of 2003, vaginal discharge specimens were collected from 1767 women aged [15-50] in 6 cardinal hospitals in Jeddah city of Saudi Arabia. The samples were examined for Trichomonas vagincilis, a prevalence rate of 12 [0.7%] were positive. Demographic characters did not show significant relation to the infection rate. All accompanied symptoms were insignificant [P > 0.05] except the vaginal consistency which was significant [P < 0.05]. The studied risk factors were insignificant to the T. vaginalis infection. So, the symptoms were neither reliable to diagnose the vaginal trichomoniasis nor specific underlying factors provoke the infection

Trematodes of fishes from the Red Sea: two new species of lepidapedon stafford, 1904 [lepocreadiidae]

Two new species of Lepidapedon are described, L. sammari n.sp. from Holocentrus sammara differs from other related species in the size of eggs, in having short prepharynx and oesophagus and the position of acetabulum. L. spiniferi n.sp. from Holocentrus spiniferus can be distinguished from L. sammari by its large size and the position of seminal receptacle