ABSTRACT
It was reported that the refractive power in the premature infants was more frequently myopic than in the normal, but there was little known about the onset and pathogenesis. The 106 premature infants, less than 37 weeks's gestational age, were comparatively examined at the age of 4 weeks to determine that there was myopic shift before cicatrical ROP state and the correlation of corneal diameter, axial length with refractive errors. The No-ROP group was 70 infants(140 eyes), and ROP group was 36 infants(72 eyes), and it was possible to analysis statistically only within the 33-36 post-conceptional age because the two groups were not normally distributed. The mean spherical equivalents at the 33-34 weeks were +1.91 Diopter, +1.48 Diopter in the No-ROP group and -0.21 Diopter, 0.00 Diopter in the ROP group, and this was statistically different(p0.05). This study revealed that the refractive errors in the ROP group were more myopic shift than in the No-ROP group in regard to early active state of ROP.