The Relationship between Anger Expression and Its Indices and Oral Lichen Planus / 전남의대학술지

Oral lichen planus (OLP) is a common inflammatory disease with unknown etiology. Depression, stress and anxiety are psychological factors that their influence on the expression of lichen planus by affecting the immune system's function has been confirmed. There is a probable relationship between anger and OLP expression. Therefore, the present study aimed to evaluate the association of "anger" and OLP. In this descriptive study 95 subjects were included in 3 groups. A: patients with oral lichen planus, B: positive control, C: negative control. Anger and its indices were assessed by the State-Trait Anger Expression Inventory-2 (STAXI-2) questionnaire, and pain was measured via the Visual Analogue Scale (VAS). The collected data were analyzed statistically using SPSS 18 software. The lichen planus and positive control groups bore higher total anger index (AX index) values compared with the negative control. Comparing anger expression-in (AXI) among the lichen planus and negative control groups revealed higher grades in lichen planus group. Evaluating the pain severity index (VAS) data and anger indices in lichen planus group, Spearman's Rank Correlation Test revealed a significant correlation between TAngR (reactional anger traits) and pain severity. The findings of this study indicated that there was a significant correlation between anger control and suppression of lichen planus development. On the other hand, the patients with more severe pain mostly expressed their anger physically. Based on the findings, we can make the claim that anger suppression and its control-in (gathering tension) may play a role in the development of lichen planus as a known psychosomatic disorders.

Extramedullary plasmacytoma of the oral cavity in a young man: a case report

Extramedullary plasmacytomas are rare solitary soft tissue tumors that arise from proliferations of malignant transformed monoclonal plasma cells and can be diagnosed through biopsy and histopathologic examination. These lesions are closely associated with multiple myelomas, which should be ruled out in all these cases by necessary laboratory and radiographic examinations. A 25-year-old man was referred to our clinic with a rapidly-growing painless lesion measuring about 2.5×3×3 cm in the palatal side of the left maxillary second and third molar teeth. A diagnosis of solitary plasmacytoma was made on the basis of clinical, radiographic, and histopathological findings. Early diagnosis of extramedullary plasmacytomas is of great importance. Radiotherapy is the common modality of treatment with or without adjuvant chemotherapy. Progression to multiple myeloma is possible; thus, close follow-up of the patient is essential after completion of the therapeutic procedure

Palifermin and chlorhexidine mouthwashes in prevention of chemotherapy-induced mucositis in children with acute lymphocytic leukemia: a randomized controlled trial

Statement of the Problem: Over the past three decades, significant improvements have been achieved in the survival of children with cancer. However, the considerable morbidity which occurs as a result of chemotherapy often restricts the treatment intensity. One of the important dose-limiting and costly adverse effects of cancer therapy is mucositis. Children with hematological malignancies are greatly at risk of developing mucositis

Purpose: This study aimed to assess the effectiveness of palifermin in preventing mucositis in children with acute lymphocytic leukemia [ALL] who undergo chemotherapy

Materials and Method: In this clinical trial, 90 children with ALL were randomized to receive chlorhexidine [n=45] or palifermin [n=45]. One group received 60 micro g/ kg/ day palifermin as an intravenous bolus once daily for 3 days before and 3 days after the chemotherapy. Chlorhexidine mouthwash was administered once daily for 3 days before and 3 days after the chemotherapy. The world health organization [WHO] oral toxicity scale was employed for grading the mucositis. The data were analyzed by using two-way ANOVA

Results: The two groups were matched for age and gender. The study groups were significantly different in terms of mucositis grading [P values after 1 and 2 week therapy were 0.00]. Palifermin decreased the incidence and severity of chemotherapy-induced mucositis

Conclusion: Palifermin reduces the oral mucositis in children with ALL. Several mechanisms of action are suggested for keratinocyte growth factor [such as palifermin] including promotion of cell proliferation and cytoprotection, restraining the apoptosis, and changing the cytokine profile

The Relationship between Anger Expression and Its Indices and Oral Lichen Planus / 전남의대학술지

Oral lichen planus (OLP) is a common inflammatory disease with unknown etiology. Depression, stress and anxiety are psychological factors that their influence on the expression of lichen planus by affecting the immune system's function has been confirmed. There is a probable relationship between anger and OLP expression. Therefore, the present study aimed to evaluate the association of "anger" and OLP. In this descriptive study 95 subjects were included in 3 groups. A: patients with oral lichen planus, B: positive control, C: negative control. Anger and its indices were assessed by the State-Trait Anger Expression Inventory-2 (STAXI-2) questionnaire, and pain was measured via the Visual Analogue Scale (VAS). The collected data were analyzed statistically using SPSS 18 software. The lichen planus and positive control groups bore higher total anger index (AX index) values compared with the negative control. Comparing anger expression-in (AXI) among the lichen planus and negative control groups revealed higher grades in lichen planus group. Evaluating the pain severity index (VAS) data and anger indices in lichen planus group, Spearman's Rank Correlation Test revealed a significant correlation between TAngR (reactional anger traits) and pain severity. The findings of this study indicated that there was a significant correlation between anger control and suppression of lichen planus development. On the other hand, the patients with more severe pain mostly expressed their anger physically. Based on the findings, we can make the claim that anger suppression and its control-in (gathering tension) may play a role in the development of lichen planus as a known psychosomatic disorders.

Knowledge and attitude of dental precatitioners in Tabriz regarding infaction control procedures

Blood-borne infections such as hepatitis B, hepatitis C and HIV might be transmitted from one individual to another during dental procedures. Therefore, sterilization and personal protection procedures are of utmost significance in dental offices. The importance of awareness of crossinfection and antiseptic principles lies in the fact that in most cases it is not possible to identify patients with hepatitis or AIDS. The aim of the present study was to evaluate awareness of infection control procedures among dental practitioners in Tabriz. In this descriptive study, 150 dental practitioners working in clinics and private offices of Tabriz were randomly selected. Data was collected by means of a self-administered questionnaire, which included respondents' personal profile and questions on infection control and sterilization methods. There were no statistically significant differences in the level of knowledge between male and female dental practitioners regarding infection control; however, there was a decline in awareness as age increased. The results of the present study suggest that in some cases dental practitioners neglect the principles for personal protection and cross-infection control. Therefore, our society is subject to widespread infection in dental offices and clinics. This potential risk necessitates careful monitoring along with government support of treatment procedures, the inclusion of infection control costs into treatment expenses and an emphasis on continuing education about infection control procedures through seminars and congresses