biostimulant effect of diode laser on acceleration of tooth eruption in children

This study was conducted to evaluate the biostimulant effect of diode gallium arsenide laser on the rate of eruption of permanent teeth in a group of Egyptian children. The laser beam was directed to an area apical to the dental follicle of the erupting tooth. The results revealed an evident acceleration in the rate of occlusal movement of the lased premolars. This can be considered as a consequence of the biostimulant power of laser on the alveolar bone apical to the erupting premolar as well as the dense connective tissue forming the dental follicle

role of adenosine receptors on the experimental induced atherosclerosis in the rabbits "pharmacological and histological studies"

Stimulation of adenosine receptors leads to inhibition of lipolysis, through decrease in cyclic adenosine monophosphate, in the fat cells of several species including humans. The present study was designed in a trial to answer the, question that, if the drugs modulating the cAMP-adenosine receptor system are capable of playing a role in hyperlipidemic or even atherosclerotic states?? The study was done on 60 white New Zealand rabbits weighing 22.5 Kg. They divided into two groups. Each consisted of 30 rabbits. The first group was non cholesterol fed rabbits while the 2nd group was cholesterol fed rabbits to induce atherosclerosis.In non cholesterol fed rabbits dipyridamole significantly suppressed serum cholesterol and triglycerides levels when compared to control non cholesterol fed rabbits. These effects were proved to be reversed by an adenosine receptor antagonist [theophylline]. In cholesterol fed rabbits dipyridamole similar to nicotinic acid suppressed the elevated serum cholesterol and triglyceride levels at 2nd, 4th and 8th weeks intervals. These effects of dipyridamole were also reversed in cholesterol fed rabbits treated with theophyllin in addition to dipyridamole.The light and electron microscopic examinations of aortic transverse sections from cholesterol fed rabbits showed the atherosclerotic pictures including fatty infiltration in the three layers of aorta, marked shedding or protrusion of the endothelial cells of tunica intima, filling of the subendothelial spaces with cell debris, irregular disarrangement of collagen and elastic fibres in tunica media with ramification of its smooth muscle cells and lastly fragmentation of the tunica adventitia. Dipyridamole in cholesterol fed rabbits prevented development of these atherosclerotic lesions in aortic sections. These effects were overcome in cholesterol fed rabbits taking theophyllin in addition to dipyridamole .Some manifestations of atherosclerosis as elevation of arterial blood pressure, decrease in coronary blood flow and myocardial contractility were also studied in the present work. Dipyridamole as well as nicotinic acid significantly improved these manifestations when compared with control cholesterol fed rabbits or those medicated with theophylline alone or combined with dipyridamole. It is concluded that dipyridamole [adenosine receptor agonist] suppressed markedly serum cholesterol and triglycerides levels both in cholesterol and non cholesterol fed rabbits. It also was proved to have a role in preventing development of atherosclerosis and its manifestations in cholesterol fed rabbits.These effects were abolished by adenosine receptor antagonist [theophyllin]

Cytogenic study in some cases of infertile men

A chromosoamal study, sex chromatin test and Semen analysis were done for 30 fertile and 50 infertile cases. The results of the last catagorie were classified according to their Semen analysis into azoospermic, oligozoospermic, terotozoospermic, asthenozoospermic and normozoospermic groups. The azoospermic and oligozoospermic groups showed marked increases of chromosomal anomalies; while the teratozoospermic and asthenzoospermic groups the chromosomal aberrations were less marked in comparasion to the control group. The results and the possible role of chromosomal aberrations in infertility were discussed