Survey on association between mycoplasma hominis endocervical infection and spontaneous abortion using polymerase chain reaction

Background: Mycoplasma infections are suggested as etiology of adverse pregnancy outcomes

Objective: The aim of this study was to evaluate the association of Mycoplasma hominis [M. hominis] infection and spontaneous abortion among pregnant women

Materials and Methods: In this case-control study that was conducted from August 2012 to January 2013, totally, 109 women were included with spontaneous abortion with gestational ages of 10-20 weeks [Cases], and 109 women with normal pregnancy with gestational ages between 20-37 weeks [Controls] in Sanandaj, Iran. Using specific primers and extracted DNA from endocervical swabs, a PCR test was conducted for detection of M. hominis infection in women. For comparison of qualitative and quantitative variables, independent Fisher tests were used and p<0.05 was considered significant

Results: The total frequency of M. hominis infection was 6 [2.75%] in women. The frequency of M. hominis infection was 2 [1.83%] in the case group [spontaneous abortion] and 4 [3.66%] in the control group, respectively. In both case and control groups, no association was seen between M.hominis infection and spontaneous abortion [OR=0. 49, CI 95%: 0.08-2.73, p=0. 683]

Conclusion: M. hominis was positive in the genital tract of some pregnant women, but it was not associated with spontaneous abortion. However, to prevent adverse pregnancy outcomes in women, foetus and neonate, routine screening and treatment for the genital Mycoplasma is recommended

Spontaneous uterine rupture after abdominal myomectomy at the gestational age of 20 weeks in pregnancy: a case report

Background: Uterine rupture in pregnancy is rare and often could be life threatening and catastrophic. Myomectomy is one of very common surgeries in gynecology, performed as the vaginal, abdominal and laparoscopic surgeries. Pregnancies occured after abdominal and laparoscopic myomectomy are high risk for uterine rapture

Case: Patient was a 28 Years old female, pregnant woman at the 20 wks of gestational age with abdominal pain and a history of abdominal myomectomy 6 yrs ago. Uterus was ruptured and fetus in amniotic sac was found in abdominal cavity

Conclusion: Early diagnosis of uterine rupture after myomectomy can save patients from death