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2.
JCPSP-Journal of the College of Physicians and Surgeons Pakistan. 2008; 18 (9): 576-577
in English | IMEMR | ID: emr-102969

ABSTRACT

The spectrum of plasma cell neoplasm represents indolent conditions like Monoclonal Gammopathy of Undetermined Significance [MGUS] to more aggressive multiple myeloma and plasma cell leukemia. Non-secretory myeloma comprises less than 01% of this spectrum where serum protein electrophoresis and quantitative immunoglobulins remain essentially normal. We are presenting a case report of this rare variant involving the sternum of an adult male


Subject(s)
Humans , Male , Hypergammaglobulinemia , Blood Protein Electrophoresis , Skull/diagnostic imaging , Tomography, X-Ray Computed , Myeloma Proteins , Antineoplastic Agents, Alkylating , Multiple Myeloma/complications
3.
JCPSP-Journal of the College of Physicians and Surgeons Pakistan. 2008; 18 (3): 176-178
in English | IMEMR | ID: emr-100294

ABSTRACT

Imatinib mesylate is a BCR-ABL tyrosine kinase inhibitor used in the management of chronic myeloid leukemia. It is a safe and well-tolerated agent with a few manageable side effects. We are reporting a case of imatinib-related fatal bone marrow aplasia after complete cytogenetic response


Subject(s)
Humans , Male , Pyrimidines/adverse effects , Piperazines/adverse effects , Protein-Tyrosine Kinases/antagonists & inhibitors , Leukemia, Myelogenous, Chronic, BCR-ABL Positive/drug therapy
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