[ role of bisphosphonate in the treatment of bone metastases from prostate cancer]

Bone metastasis is very frequent in prostate cancer. It is a turning point that marks the severity of the disease. Before metastasis become symptomatic, treatment preventing bone events should be indicated. To evaluate the role of bisphosphonate in the treatment of bone metastases from prostate cancer. A review of literature. Bisphosphonates play a very important role to prevent bone mass loss and to reduce bone complication events. Bisphosphonates are recommended as preventive treatment at the time of diagnosis of bone metastatic prostate cancer

Circumcaval ureter with a synchronous ipsilateral transitional cell carcinoma of the upper urinary tract and the urinary bladder

We report a case of concomitant ureteral transitional cell carcinoma [TCC] developed in a circumcaval ureter associated to an invasive bladder cancer. Diagnosis was made by intravenous urography [IVU] and contrast-enhanced computed tomography [CT] scanner which showed a typical [J] shaped deformity in the dilated proximal ureteric segment with moderate right hydronephrosis and pelvic filling defect associated to bladder filling defect due to a bladder tumor. The patient underwent a radical cystoprostatectomy and nephroureterectomy; no recurrence was detected after a 12 months period of follow-up