ABSTRACT
Objective: To determine frequency of rotavirus infection in children under 2 years of age presenting with acute watery diarrhea at tertiary care hospital. Study Design: Cross sectional study. Place and Duration of Study: Department of Pediatrics, MH Rawalpindi, from Jan to Jun 2016
Material and Methods: Total 246 children, hospitalized with complaints of non-bloody acute watery diarrhea at the time of admission were included. Stool samples were collected and transported to Armed forces institute of Pathology [AFIP] for stool antigen detection for Rotavirus. Descriptive statistics were calculated. Stratification was done and post stratification Chi-square test was applied. A p-value <0.05 was considered as significant
Results: There were 48.8% [120] male and 51.2% [126] female children. Mean no. of stools per day were 6.62 +/- 1.92 in children whose stools for Rotavirus antigen were positive in 174 [70.7%] patients, no. of stools per day was significantly associated with positive results
Conclusion: Rotavirus was found to be positive in majority of children causing substantial morbidity. There was significant association of rotavirus infection with increased no of watery stools per day
ABSTRACT
To determine the frequency of hepatitis-C virus infection in patients on maintenance haemodialysis in Nishtar Hospital Multan. Simple descriptive cross sectional. Thirty patients of maintenance haemodialysis for atleast six months twice daily haemodialysis were included. From April 2003 to March 2004. Thirty patients out of whom 20 were male and 10 were female. Patients between the age of 16 to 60 were included in the study. All the patients were on haemodialysis for more than six months and were receiving dialysis therapy twice week. Diagnosis of HCV infection was made by detection of HCV antibody with the help of kit. Name of the kit used was ACON hepatitis C Virus Rapid Test Strip [Serum]. This was a qualitative membrane based immunoassay for the detection of antibody to HCV in serum. Frequency of anti HCV among patients of maintenance haemodialysis was found to be 26.7% [8/30]. Role of different risk factors for the transmission of HCV during haemodialysis were quite conclusive. History of blood transfusion and duration of haemodialysis were the main factors in transmission of anti HCV to the patients of maintenance haemodialysis. The Frequency of anti HCV among patients on maintenance haemodialysis was 36.7%