Epidemiological evaluation of head and neck Sarcomas in Iran [the study of 105 cases over 13 years]

Background: Head and neck sarcomas are exceedingly rare and they include 4% - 10% of all sarcomas and less than 1% of all neoplasm of head and neck

Objectives: The aim of this study is to evaluate the epidemiological characteristics of head and neck sarcomas of patients in Isfahan, Iran

Patients and Methods: In this retrospective study, from the 16000 patients whose files were evaluated, the total number of 105 head and neck sarcomas were collected. They were evaluated with due attention to age, gender of the patients and the most common location of the lesion

Results: From the total number of 105 [0.6%] patients with sarcomas, 56 were men [53.33%] and 49 women [46.66%]. The most common head and neck sarcomas among this population were Osteosarcoma [32 cases, 30.47%], Chondrosarcoma [14 cases, 13.33%], and Ewing sarcoma [11 cases, 10.47%].The most common soft tissue sarcoma was Rabdomiosarcoma. Mandible was the most common location for these lesions

Conclusions: In this study, the hard tissue sarcomas were more prevalent than soft tissue ones. Hence, special attention should be paid to the patients when being diagnosed

Granulocytic sarcoma [chloroma] presenting as multiple sites in oral cavity: report of a case

Granulocytic sarcoma [GS] is an unusual extramedullary tumor, is composed of immature granulocytic precursor cells. The intraoral occurrence of this tumor is extremely rare. Here we report a case of GS with palatal swelling, gingival lesions in maxilla and mandible and aleukemic presentation in a 45 years old male

Epithelial dysplasia in oral cavity

Among oral lesions, we encounter a series of malignant epithelial lesions that go through clinical and histopathologic processes in order to be diagnosed. Identifying these processes along with the etiology knowledge of these lesions is very important in prevention and early treatments. Dysplasia is the step preceding the formation of squamous cell carcinoma in lesions which have the potential to undergo dysplasia. Identification of etiological factors, clinical and histopathologic methods has been the topic of many articles. This article, reviews various articles presenting oral cavity dysplasia, new clinical methods of identifying lesions, and the immunohistochemical research which proposes various markers for providing more precise identification of such lesions. This article also briefly analyzes new treatment methods such as tissue engineering