Cardiac markers responses to coronary bypass graft (CABG) surgery with cardio pulmonary bypass and aortic clamping

Quantitive assessments of serum cTnl, CK-MB in 106 coronary bypass graft (CABG) patients at base line after anesthesia induction; at the end of operation, and at every 6 hours during the first 24h post-operation and then, on 2nd, 3rd, and 5th postoperative day. The serum cTnl and CK-MB significantly increased from the end of the surgery to 5th postoperative day with the peak value (50.82 ± 31.72 mg/ml and 70.78 ± 64 UI/ml, respectively) reached on average 8-10h after the aortic unclamping. The aortic cross-clamping time correlated slight positively to the pear of the serum cTnl and CK-MB on the first postoperative day. The finding showed that the postoperative increase of cTnl levels in the CAGB patients resulted from several factors. The most important contributing factor was the cross clamping time, other ones were the cardioplegia types

Efficacy of anesthesia with sufentanil-propol for coronary artery bypass

Study on 198 cases of coronary artery bypass surgery at Heart Institute of Ho Chi Minh city. There were 146 males and 52 females; mean weight: 59.46±9.37kg, mean age: 61.51±8.20 years old, the mean time of cardiopulmonary bypass: 155.07±36.28 minutes, the mean time of aortic clampage: 93.36±23.09 minutes, average number of coronary artery bypass grafts: 3.23±0.86, the mean time of extubation: 8.26±1.97 hours, the mean day of ICU length stay: 1.8±2.3 days, the mean day of hospital length stay: 17.93±8.5 days. These findings showed that the introduction of new anesthetic drugs with fast effectiveness and short duration of anesthesia could help to have rapid intubations, hemodynamic stability, and early extubation, to ensure patients’ safety, even in emergency operations or cardiac dysfunction patients

The use of dispase and trypsine solution to detach cells from fetal monkey kidneys

The study on using dispase and trypsine 0.25% to detach cells from fetal monkey kidneys of Macaca mulatta showed that: the detach ability of dispase was much higher than trypsin. Some characteristics of dispase were suitable for detaching fetal cell in cold condition or serum condition. However, dispase has not been used as commonly as trypsin. Dispase can not be a good solution to detach cells without the effect of trypsin