ABSTRACT
Introduction: The spleen is a lymphoid organ that plays an important role in the body's defense against organisms, participation in blood filtration process, phagocytosis and immunoglobulin production. When splenectomy due to severe splenic trauma or hematological disorder is inevitable, spleen autotransplantation may be the only option to preserve the spleen. It has not been determined the structural rearrangements after transplanting in comparison with the amount of transplanted spleen. The aim of this study was to evaluate the histological changes of spleen autotransplanted in the omentum of rats.Materials and Methods: In this experimental study, 16 male Wistar rats underwent splenectomy and transplanting three pieces of splenic tissue consists of 10-15% of the greater omentum. The rats were divided to two equal groups; Eightcaseswere randomly separated and followedfor 6 months (Group Au-6) and 8 other cases also were separated for 12months'follow-up (group Au-12). At the end of follow-up period, after the re-operation ofautotransplanted rats, the splenictissues underwent the macroscopic and microscopic examination and two groups were compared together.Results: After laparotomy, splenic tissues were detected in all cases (8/8, 100%) of Au-6 group and 7 cases (87.5%) of Au-12 group. It’s observed no significant difference between two groups in the capsule around splenic tissue, organized structure, fibrosis and revascularization (P>0.05).The hemosiderinpigmentation was significantly higher in Au-12 group (P=0.03).Conclusions: The results of this study showed that autotransplanting about 15 percent of splenic tissuewere associated with a high success rate in tissue structure rearrangement.Therefore, spleen autotransplantation even in small sizes was highly recommended in cases of unavoidable splenectomy
ABSTRACT
Objectives: Cryptorchidism is the most frequent birth anomaly in boys with 2-5% prevalence in full term infants. This anomaly is associated with an increased risk of testicular cancer and infertility as well as hernia, testicular torsion, and psychological distress. Surgery is the main treatment for this anomaly. This study aimed to evaluate the therapeutic efficacy of laparoscopic orchiopexy in the treatment of non-palpable undescended testis. Methods: Forty patients with a non-palpable testis were evaluated by laparoscopic orchiopexy in a hospital in Hamedan city, Iran, during 2006 to 2009. The average age of patients was 19±12.16 months old. The patients were followed up after the surgery and three months later to assess the response to treatment and the testicular atrophy. Results: Thirteen patients did not have a testis in the laparoscopic investigation and six patients had testis located in the inguinal canal. So they were excluded from the analysis. Seventeen patients were treated by one-staged laparoscopic orchiopexy while four patients were treated by two-staged Fowler-Stephens laparoscopic orchiopexy. The success rate for the treatment was 100%. Conclusion: Laparoscopic orchiopexy is a safe and effective method for the treatment of non-palpable undescended testis.
ABSTRACT
Although Laparoscopic Cholecystectomy [LC] is one of the most common elective surgeries, its indication in acute cholecystitis is controversial. This retrospective study is comprised of 182 patients with acute or chronic cholecystitis admitted at Ekbatan and Tamin Ejtamaiee hospitals and underwent laparoscopic Cholecystectomy from March 2002 to September 2006. Patients were divided into two groups: 1- patients with acute cholecystitis and 2- patients with chronic cholecystitis on the basis of surgical and pathological findings. Patients were compared for laparoscopic cholecystectomy results, complications, duration of hospital stay, and factors associated with conversion from laparoscopic cholecystectomy to open cholecystectomy. From 182 patients underwent LC, 39[21.4%] were male and 143 [78.6%] were female. The mean age of patients was 49 +/- 15.9 years [17-85 year]. The mean age of patients with acute cholecystitis who underwent LC was significantly lower than those with chronic cholecystitis [p<0.05]. The conversion rates was significantly higher in the acute cholecystitis group [p<0.05]. Adhesion was the main reason for conversion to open surgery which was found in 16 [72.7%] patients. The conversion rate was 13.6% for adhesion plus hydrops, 9% for edema and 4.5% for pancereatic head cancer. This study showed that LC is an appropriate safe method for treatment of cholecystitis and can be served as the method of choice and first line therapy for cholecystitis