ABSTRACT
Objective@#To present a rare case of primary intraosseous carcinoma arising from the mandible and to discuss the ensuing course and the management of the patient. @*Methods@#Design: Case Report. Setting: General Tertiary Government Training Hospital. Patient: One. @*Result@#A 56-year-old man consulted for a right mandibular mass of 4 months that started as a small bony swelling which gradually increased to its present size of 8 x 6 cm. Incisional biopsy revealed invasive squamous cell carcinoma and the patient underwent segmental mandibulectomy and bilateral selective neck dissection (levels 1 to 3). Final histopathologic findings revealed squamous cell carcinoma. @*Conclusion@#Primary intraosseous carcinoma of the mandible was diagnosed since there was no overlying mucosal ulceration, other types of odontogenic carcinoma were ruled out, and no other distant primary tumor was noted from the time of examination until six months post-treatment.