ABSTRACT
Clinical data from 175 patients with squamous cell carcinoma of the oesophagus or cardia admitted to Songklanagarind Hospital between 1982 and 1988 were analysed to evaluate the effects on survival of various tumour and treatment variables. Most tumours (greater than = 86%) were in stage III or IV. Forty-seven percent of stage-IV tumours and 99 per cent of those in stages I, II or III were resectable. One-year and 3-year survival rates of resected stage-III patients (57.3% and 27.5%) were significantly higher than those of resected stage-IV patients (33.3% and 0%). Resection conferred no benefit over radiotherapy chemotherapy or no treatment on the survival of stage-IV cases beyond one year. Combined chemotherapy/radiotherapy/resection of stage-III and stage-IV patients gave no statistically significant improvement in survival. Among resected patients, only lymph node involvement was associated with significantly lower survival (relative risk compared to no involvement = 2.3, 95% CL: 1.2, 4.6), while the fungating type of tumour was possibly associated with improved survival (relative risk compared with all other types = 0.24, 95% CL: 0.05, 1.1).
Subject(s)
Adult , Aged , Aged, 80 and over , Carcinoma, Squamous Cell/epidemiology , Combined Modality Therapy , Esophageal Neoplasms/epidemiology , Female , Follow-Up Studies , Hospitals, University , Humans , Male , Middle Aged , Neoplasm Staging , Risk Factors , Survival Rate , Thailand/epidemiologyABSTRACT
366 cases of carcinoma of the oesophagus in Songklanagarind Hospital, from February 1982 to August 1987, were studied. There were 274 male and 92 female patients, Male to female ratio was 2.97:1. Mean age was 62.58 years with mean age in male patients 63.59 and female 59.62. There were 45 Muslim patients (12.3%). Location of tumour was most common at the midthoracic portion (50.98). There were 111 patients from Songkhla, 57 from Nakhon Si Thammarat, 40 from Phatthalung, 39 from Trang, 27 from Narathiwat, 23 from Pattani, 18 from Yala, 17 from Surat Thani, 10 from Krabi, 10 from Satun, 5 from Phuket, 4 from Phangnga, 2 from Ranong and 1 from Trat, Chumphon, Bangkok. The incidence at tumour for males in Songkhla was 3.27/100,000 and the incidence of frmales was 0.92/100,000.