ABSTRACT
Background: India is a hyper-endemic zone for malaria. We need tests which can be done easily and are cost effective to assess the severity of the disease and to help in prognostication. CRP is one such investigation which can be used. Aims And Objectives: We carried out this prospective study to find the correlation between the level of CRP and the complications in patients of P.vivax and P. falciparum malaria. Material and Methods: Level of C- reactive protein, was measured in 227 patients of P.vivax and P. falciparum malaria, admitted in GMERS medical college Gotri, Vadodara. It was then compared with single and multiple complications as well as with the duration of hospital stay in both vivax and falciparum patients.Statistical analysis was done using Chi-Square test, unpaired T-test and ROC curve. Results: Out of 227 patients,105(46.2%) had P.vivax and 122(53.7%) had P. falciparum malaria. CRP level was high in all patients. In vivax and falciparum patients with single complications, the mean CRP level was 24+11.6 mg/L and 24.1+6.2 mg/L respectively. Both types of malaria with multiple complications showed very high levels, 69.6 + 14.1mg/L in P.Falciparum and 71.6 + 6.5mg/L in P.vivax patients. Elevated CRP level (41.5 mg/L) also predicted a prolonged hospital stay. Conclusion: Our study corroborates the observation that high CRP level has a strong prognostic value for predicting the complications in malaria.
ABSTRACT
Introduction: Number of blind people in the world is 45 million. Out of which 5.4 million blind people are in our country. Corneal ulcer is a major cause of blindness throughout the world. About10% cases of blindness are due to corneal ulcer. Aim:To detect antibiotic sensitivity Pattern of causative bacteria responsible for corneal ulcer. Material and mathod: 150 samples were collected during period of 1 year from clinically diagnosed cases of corneal ulcer at SSG Hospital, Baroda.Results: Total 150 samples were tested for antibiotic sensitivity pattern and among them Gram positive bacteria showed highest sensitivity to ciprofloxacin and among Gram negative bacteria showed highest sensitivity to ciprofloxacin, gatifloxacin and amikacin while pseudomonas showed highest sensitivity to imepenem.
ABSTRACT
Objective: Hepatitis is a major public health problem throughout the world affecting several hundred million of people. Aim is to study incidence of HIV seropositivity in blood donors and suspected patients attending voluntary council and testing centre and to compare prevalence of Anti HCV antibody positivity in HIV seropositive samples. Material and Methods: A total of 1786 serum samples were tested for HIV antibodies in patients attending Voluntary Council and Testing Centre (VCTC) at Guru Govind Singh Hospital, Jamnagar. The serum sample of HIV seropositive patients were tested for HCV antibodies. Those serum samples found positive for Anti-HCV antibody were reconfirmed by Signal HCV method. Out of total 1786 samples for HIV 297 patients were positive (16.63%) for HIV and 1489 patients were negative (83.37%) for HIV. Discussion: As the hepatitis C virus has capacity to induce chronicity that leads to cirrhosis and liver cancer in long term. In the absence of vaccine and effective chemotherapy, screening of more and more serum samples is the only way to prevent post transfusion hepatitis C virus infection.
ABSTRACT
Background: Although prevalence of MRSA strains is reported to be increasing, there are scanty studies of their prevalence in community acquired pyoderma in western India. Aims: This study aimed at determining clinicobacteriological profile & prevalence of Methicillin Resistant Staphylococcus aureus (MRSA) infections in community acquired pyoderma. Materials and methods: Prospective study was carried out in tertiary care hospital in Baroda.100 patients with pyoderma, visiting outpatient department of dermatology, were studied clinically and microbiologically. Sensitivity testing was done for gram positive & gram negative organisms by disc diffusion method. MRSA were detected by Agar dilution method. Result: Primary pyoderma accounts for 64% of cases with highest number of cases were of Impetigo (26%). The culture positive rate was 83% with Staphylococcus aureus being the major pathogen. (78.82%) Out of these 10.45% strains of Staphylococcus aureus were Methicillin Resistant Staphylococcus aureus. (MRSA) Conclusion: MRSA as a cause of pyoderma is a reality albeit in present study group. All the MRSA isolated were sensitive to Vancomycin. Sensitivity to Amoxyclav, Fluoroquinolones & Macrolides is quite good, which can be used for treatment.