ABSTRACT
Background: Oral cavity has various pathogens and most of the denture wearers are older individuals with impaired ability to clean denture and there are conditions where prescription of adhesive is must, which in turn can act as biofilm for growth of Candida. As there are contradictory review on use of adhesive there is a need to study the affect of denture adhesive on candidal growth. Methods: In this randomised clinical trial 24 healthy individuals were randomly recruited. These 24 were divided into 2 groups of 12 individuals each. Group 1 subjects were given powder form of adhesive and group 2 subjects were given paste form of adhesive. Baseline sample (swab) was taken from palate and saliva. After 15 days of use of adhesive, three samples (swab) were taken from palate, saliva and tissue surface of denture. These samples were further subjected to microbiological analysis. Results: Both the groups showed significant increase in candidal growth. Conclusion: This study advocates that denture adhesive do promote the growth of Candida. This could also be due to impaired manual dexterity of the individual or improper hygiene.