effect of full crown preparation on normal and inflamed pulp tissue: an animal study

Full crown preparation may have adverse effects on pulp tissue. In this study, the effect of full-crown preparation on intact versus inflamed pulp tissue was studied. Fifteen healthy mature cats were randomly selected for this study. The study was performed on four canine teeth of each cat. Cats were anesthetized and then radiographs were taken from the canine teeth. Class V cavities were prepared in cat canine teeth. Soft decayed dentin was placed on the floor of cavities and sealed. After 1 month, all of the samples prepared for crown fabrication. Before crown preparation, an impression was taken in a custom tray. During crown preparation, the remnants of carious dentin were removed and undercuts were sealed by glass-ionomer. After preparation, self-cured acrylic temporary crowns were fabricated in a direct procedure and cemented permanently by glass-ionomer. One week later, teeth of the opposite jaw were prepared in a similar procedure. After 2 months, vital perfusion performed and the pulp tissue was histologically examined. There was no significant difference between 4 groups, regarding to histologic status of the pulp. In healthy lower jaw, inflammation was the most frequent but in the other groups, necrosis was most frequent. Also, there was no significant difference between the upper jaw and the lower jaw groups regarding to the frequency of necrosis and inflammation. There is no significant difference between intact and inflamed groups regarding the frequency of necrosis and inflammation

Comparative assessment of nuclear and nucleolar cytochemical parameters of oral epithelial cells in smokers and non-smokers by methyl green-pyronin staining

A strong relationship exists between cigarette smoking and the development of oral squamous cell carcinoma. Smoking can significantly increase cellular proliferation. Nevertheless, there is little reference in literature to the cytological assessment of oral mucosa in this respect. Changes in nuclear and neucleolar cytomorphometric parameters such as diameter, surface, number and color intensity, in cytologic smears which were collected from normal buccai mucosa of 30 cigarette smokers and 30 non smokers, using methyl green-pyronin staining were studied. Our findings attested to smoking as significant inductive factor in cytochemistry as well as morphologic changes. This technique is a valuable tool

Calcifying odontogenic cyst with complex odontoma: histological and immunohistochemical features

The calcifying odontogenic cyst [COC] is a rare odontogenic cyst. Only 2% of all odontogenic cysts and tumors are COC. COC associated with odontoma [COCaO] reported in 24% of COCs. COCaO presents a greater incidence in female, with a ratio of 2 to 1. The highest incidence of COCaO occurs during the second decade with a mean age of 16 years, most frequently occurring in the maxilla [61.5%]. Here, we describe a classic case of COCaO of the maxillary incisor-canine region in 17-year-old girl, and discuss the clinicopathological features and immunohistochemical finding of this tumor

[Histologic changes in rabbit temporo mandibular joint following local injection of recombinant-bone morphogenetic protein-2 [RBMP2] during mandibular advancement by bite jumper]

Mandibular deficiency is one of the most common malocclusions that is treated with functional appliances during growth periods. The aim of this study was to evaluate the histologic changes of the single local injection of rBMP2 in combination with bite jumper therapy in a rabbit model TMJ. Eighteen 8-week old Albino New Zealand white male rabbits were divided into three groups: The first group served as control and in the second and third groups rBMP2 and normal saline were injected respectively. The second and third groups had bite jumper appliance. After 8-weeks of bite jumper therapy, in the second group 12.5 microgr rBMP2 powder plus 2.5cc normal saline and in the third group only 2.5 cc normal saline was injected in the TMJs on both sides. After 16-weeks of treatment, the animals were sacrificed and the joints were examined histologically. The rBMP2 group showed greater cartilage cells and maximum condylar cartilage thickness [in the form of cartilage hyperplasia] than control and normal saline groups. The control group had the lowest disc deformity histologically and the rBMP2 group showed lower disc deformity than normal saline group. rBMP2 is able to accelerate condylar cartilage growth in the form of cartilage hyperplasia

[Clinical and demographic findings of oral exophytic lesions in patients referred to oral medicine department of Mashhad dental school-Iran [2004-7]]

Peripheral exophytic lesions are one of the most prevalent oral lesions and the most important cause of patients's referral to oral medicine department. Determination of frequency of oral peripheral exophytic lesions and demographic findings and clinical presentation can help us for diagnosing, prevention and management of them, so a retrospective 4-year study was carried out by purpose of determining the frequency of different types of peripheral exophytic lesions in patients referred to oral medicine department of Mashhad Dental School. Descriptive and retrospective study was done on files of 166 patients with peripheral exophytic lesions referred to oral medicine department of Mashhad Dental school from 2004-2007. Demographic [Age, sex ...], clinical [size, number, location] and histopathological data were recorded and described by SPSS software and descriptive statistical analysis and table and charts prepared. In our study, peripheral exophytic lesions were more frequent among females [F/M: 3/2]. The mean age of patients was 40-60 years [33.5%]. Gingiva was the most common location for exophytic lesions in oral cavity [44.0%]. Inflammatory hyperplasia lesions were the most prevalent peripheral exophytic lesions and SCC was also the most common tumor in oral cavity. Duration in most of lesions [71.3%] was between 1 to 12 month and the most important chief complaint of patients was swelling [76.8%]. Although most of epidemiological patterns of oral exophytic lesions were similar to other researches, this research revealed recording of clinical observations in patients' files was essential for epidemiologic studies and carefulness in clinical and histopathologic examination is necessary and leads to correct diagnosis

T-cell lymphoma of palate with nose and maxillary sinus involvement: a case report

Oral cavity T-cell lymphoma occurs rarely. This case report describes a patient with such a tumor. The case was a 75 years old man presented with a painless swelling on his hard palate mucosa. He had suffered from nose- bleeding and nasal obstruction. Pathology revealed the presence of a T-cell lymphoma tumor in the palate. Though rare, the signs and symptoms of the case suggest that T-cell lymphoma should be considered in the differential diagnosis of oral cavity lesions