ABSTRACT
Aim of the Study: was to investigate the influence of phacoemulsification on corneal endothelial cells and its injury risk factors in diabetic cataract patients and non-diabetic patients
Methods: Electronic databases were searched: Scopus, EMBASE, and Google Scholer], PubMed/MEDLINE, Scopus, The Cochrane Library, and Web of Science. Econlit from 1990 to 2017. This was completed with a manual search of references of relevant papers. Risk of bias in methodology of studies was measured using the Newcastle-Ottawa Scale
Results: Observation of corneal endothelial cell density, coefficient of variation and percentage of hexagonal cells preoperatively, 1 day, 1week, 1 and 3 months postoperatively was carried out, and multiple Logistic regression analysis for risk factors of corneal endothelial cell injury was taken
Results: Out of 779 retrieved papers, 9 studies with a total of 1129 individuals were finally included [579 diabetic eyes and 550 non-diabetic eyes]. For the dynamic changes between preoperative and postoperative values, significant differences were identified between the two groups in endothelial cell density [ECD] and hexagon cells [HC%] at 1 day, 1 week, 1 month, and 3 months postoperatively, in central corneal thickness [CCT] at 1 month postoperatively, and in coefficient variation [CV] at 1 week and 1 month postoperatively. However, no significant differences were observed in CCT at 1 day, 1 week and 3 months postoperatively or in CV at 1 day and 3 months postoperatively
Conclusion: It could be concluded from the current literature that aged-cataract patients with diabetes mellitus manifested poor tolerability to cataract phacoemulsification surgery in contrast to senile cataract patients
ABSTRACT
Background: Sugar- and artificially-sweetened beverage consumption have been connected to cardio metabolic hazard factors, which rise the danger of cerebrovascular illness and dementia
Purpose: We studied whether sugar or artificially sweetened beverage intake was related with the prospective dangers of incident stroke or dementia
Materials and methods: We studied 361 members aged more than 45 years for incident stroke [mean age 61 [SD, 10] years; 163 men] and 185 participants aged >60 years for incident dementia [mean age 68 [SD, 7] years; 85 men]. Beverage consumption was computed using a food-frequency questionnaire at cohort studies. We quantified latest consumption at investigation 7 and cumulative intake by averaging across examinations. Surveillance for incident events commenced at examination 7 and continued for 5 years. We observed 12 cases of incident stroke [10 ischemic] and 10 cases of incident dementia [8 consistent with Alzheimer's disease]
Results: After modifications for age, gender, education [for analysis of dementia], caloric consumption, diet feature, physical activity, and smoking, higher recent and higher cumulative consumption of artificially sweetened soft drinks were related with an increased risk of ischemic stroke, all-cause dementia, and Alzheimer's disease dementia. When comparing day-to-day aggregate consumption to 0 per week [reference], the risk ratios were 2.87 [95% confidence interval, 1.24-6.89] for ischemic stroke and 2.91 [95% confidence interval, 1.15-6.99] for Alzheimer's disease. Sugar-sweetened beverages were not associated with stroke or dementia
Conclusions: Artificially sweetened soft drink consumption was allied with a higher risk of stroke and dementia
ABSTRACT
Over the past few decades, vitamin D was proposed to be highly influential on female fertility and reproductive health. Its role was extensively studied and evaluated specifically in females with polycystic ovarian syndrome
Objectives: the aim of this research was to study the correlation between vitamin D and fertility in general, and in polycystic ovarian syndrome-associated infertility in particular
Methods: we searched Cochrane Library and PubMed for articles addressing the impact and role of vitamin D in fertility issues in females with polycystic ovary disease. Specifically-related topics were carefully reviewed and analyzed to summarize their conclusive results
Results and Discussion: Vitamin D was lower in females with PCOS and vitamin D administration had increased its level, improved metabolic disturbance and shortened inter-menstrual intervals in those patients. Patients with high vitamin D levels had a better success rate of invitro fertilization. However, it did not affect the time to pregnancy in PCOS women
Conclusion: Vitamin D is beneficial for improving metabolic as well as reproductive functions in women with PCOS. It is also essential for successful in-vitro fertilization, and it is probably protective against endometriosis. However, results from different studies are contradictory, and still there is no solid evidence that there is a cause-effect relationship between vitamin D and fertility