ABSTRACT
@#(T2DM) among the younger age groups is a growing concernworldwide. Thus, assessing the perception of risk andknowledge among those at risk may provide an opportunityfor early intervention, delay or even prevent the onset. Objective: The aim of this study was to determine theperceived risk of developing T2DM and its knowledgeamong the offspring of diabetic patients.Methods: A cross sectional study using a self-administeredquestionnaire was conducted among university studentswhose parents had type 2 diabetes to determine theirperceived risk and knowledge on T2DM. Results: A total of 336 university students participated inthis study and 56.5% of them correctly identified themselvesat risk of developing T2DM. About half of them (52.7%) hadhigher knowledge of T2DM. Male students appeared to havebetter risk perception (p=0.024) compared to females whilethose with mothers affected by T2DM appear to have higherknowledge regarding diabetes (p=0.007). Most of theirinformation regarding T2DM was obtained from the internet(87.5%) and other family members (77.9%).Conclusion: The students whose mothers had T2DM appearto have better knowledge and information regarding T2DMand this was mostly obtained from the internet and familymembers. Awareness regarding diabetes and healthylifestyles advice through primary patients may be beneficialfor their offspring.
ABSTRACT
The aim of this case study is to emphasize the importance of alpha-blockade in managing a rare complication of an untreated pheochromocytoma. Clinical Presentation and Intervention: A 41-year-old man with previous bilateral pheochromocytoma presented with chest pain. He was suffering from cardiac failure and persistent hypotension requiring an inotrope. Cardiac markers, an electrocardiogram and an echocardiogram confirmed acute myocardial infarct with poor ejection fraction and global hypokinesia. An [18]F-fluorodeoxyglucose PET/CT scan showed progressive left suprarenal and organ of Zuckerkandl pheochromocytomas. Blood pressure stabilisation proved challenging but was achieved by titrating an incremental dose of alpha-blocker against a tapering inotropic dose. This case showed the efficacy of an alpha-blocker despite persistent hypotension in a patient with pheochromocytoma-induced cardiomyopathy
ABSTRACT
Agranulocytosis is the most serious and potentially fatal side-efiect of antithyroid drug therapy. We report two cases presenting with carbimazole-induced agranulocyotsis. The first patient received 20 mg of carbimazole daily, and developed agranulocytosis within one month of commencementoftherapy. The second patientpresented with agranulocytosis complicated by a thyroid storm following Ingestion 60 mg of carbimazole, daily for two months. Both patients were treated with 300 mg of granulocyte colony factor [GCSF] subcutaneously [in addition to discontinuation of their anti-thyroid drugs] and broadspectrum antibiotics for neutropenic sepsis. The total white and neutrophil counts returned to baseline following five and six days of treatment, respectively, with the resolution the use of GCSF in the treatment will be being discussed