ABSTRACT
As a sequence to a cross-sectional study on the clinical gradient of the disease by Pesigan et al., (1965) a follow-up of the subjects in that study was made after 12 years. Of the 135 untreated cases followed up, 23 (17.04%) died from various causes of which 12 (8.89%) had signs and symptoms attributable to schistosomiasis as the immediate cause or one of the main causes of death. This occurred in 1 to 11 years with an average of 5 years, which corresponds roughly to 1.78% of the infected cases per year. This is considered a conservative estimate because in the other deaths due to other diseases, schistosomiasis is a contributory cause. A diminishing severity of the disease was observed among the surviving patients which could imply that they must have developed some degree of immunity to the disease.
Subject(s)
Adolescent , Adult , Age Factors , Child , Feces/parasitology , Follow-Up Studies , Hepatomegaly/etiology , Humans , Middle Aged , Philippines , Schistosomiasis japonica/mortality , Splenomegaly/etiologySubject(s)
Adolescent , Adult , Aged , Child , Child, Preschool , Drug Evaluation , Female , Follow-Up Studies , Hepatomegaly/etiology , Humans , Isoquinolines/therapeutic use , Male , Middle Aged , Praziquantel/therapeutic use , Schistosomiasis/drug therapy , Schistosomicides/therapeutic use , Splenomegaly/etiologySubject(s)
Adolescent , Adult , Child , Clinical Trials as Topic , Dose-Response Relationship, Drug , Drug Evaluation , Dyspepsia/chemically induced , Feces/parasitology , Fever/chemically induced , Humans , Isoquinolines/therapeutic use , Middle Aged , Nausea/chemically induced , Parasite Egg Count , Praziquantel/adverse effects , Random Allocation , Schistosoma japonicum , Schistosomiasis/drug therapy , Schistosomicides/therapeutic useSubject(s)
Adult , Anticonvulsants/therapeutic use , Benzenesulfonates/therapeutic use , Brain Diseases/etiology , Drug Therapy, Combination , Female , Humans , Male , Niridazole/therapeutic use , Praziquantel/therapeutic use , Schistosomiasis/drug therapy , Schistosomicides/therapeutic use , Seizures/etiologyABSTRACT
An attempt was made to estimate the annual incidence of schistosomiasis from the prevalences at ages 7 to 10 in the Philippines.