ABSTRACT
Background: Atherothrombotic cardiovascular disease is currently the leading cause of morbidity, mortality and cost burden in the medical community. New studies have found atherosclerosis to be predominantly an inflammatory reaction of vessel wall
Methodology: We conducted this review using a comprehensive search of MEDLINE, PubMed, and EMBASE, January 1987, through February 2017. The following search terms were used: Atherosclerosis, thrombotic heart diseases, hypertriglyceridemia, dyslipidemia, pathology of atherosclerosis, treatment of atherosclerosis
Aim: In this review, we evaluated the pathogenesis, risk factors and management of atherosclerosis
Conclusion: More studies must be done to offer better management, even though massive success was achieved in the past decades. Also healthy population must be encouraged to avoid risk factors that cause such pathologies
ABSTRACT
Introduction: There are many different types of primary immunodeficiency syndromes, with an overall prevalence of one in every 2,000 children in the United States. These syndromes are broadly classified as B-cell, T-cell, phagocytic, complement, or combined immunodeficiency disorders, mainly affecting children from a very young age
Methodology: We conducted this review using a comprehensive search of MEDLINE, PubMed, and EMBASE from January 1987 to March 2017. The following search terms were used: immunodeficiency syndromes, B-cell disorder, T-cell disorder, complement disorder, phagocytic diseases, diagnosis of primary immunodeficiency, newborn screening
Aim of the work: In this study we aimed to understand the various common types of primary immunodeficiency syndromes, and also study their diagnosis and screening methods
Conclusion: Early diagnosis with the help of newborn screening and data recording can help in reducing significant mortality and morbidity of children born with such disorders. Primary health care providers and pediatricians must keep a high degree of suspicion as many times the presentation can be subtle