ABSTRACT
Background: Stomatitis is the most common complication of chemotherapy. This study aimed to assess the effect of aloe vera solution on stomatitis and its pain intensity in patients undergoing chemotherapeutic procedures
Methods: In this randomized controlled clinical trial, 64 patients with Acute Myeloid Leukemia and Acute Lymphocytic Leukemia undergoing chemotherapy were randomly divided into a control and an intervention group. The intervention group patients were asked to wash their mouths with 5 ml of aloe vera solution for two minutes three times a day for 14 days. The control group patients, however, used only the ordinary mouthwashes recommended in hematologic centers. The patients' mouths were examined by two assistants on days 1, 3, 5, 7, and 14. The intensity of stomatitis was recorded according to WHO stomatitis intensity checklists and pain was evaluated using Visual Analog Scale. The data were analyzed by SPSS statistical software, version 18
Results: The results showed that aloe vera solution mouthwash significantly reduced the intensity of stomatitis and its pain in the intervention group compared to the control group. On the first day, no significant difference was found between the two groups regarding the mean intensity of stomatitis [P=0.178] and pain [P=0.154]. However, a significant difference was observed between the two groups in this regard on other days [days 3-14: P=0.001 for stomatitis intensity, P=0.001 for pain]
Conclusions: Aloe vera solution can improve the patients' nutritional status, reduce stomatitis and its pain intensity, and increase the patients' satisfaction
Subject(s)
Humans , Male , Female , Adult , Middle Aged , Aged , Stomatitis , Antineoplastic Agents , Lymphoma , LeukemiaABSTRACT
Congenital heart disease causes large expenditures as well as mental pressures for the parents and, consequently, endangers the mothers' quality of life and self efficacy. Thus, the present study aimed to determine the effect of educational program on the quality of life and self efficacy of the mothers of the infants with congenital heart disease. The present randomized controlled trial was conducted on 56 mothers who had children with congenital heart disease [28 in the control and 28 in the intervention group] in Imam Reza Clinic, Shiraz, Iran in 2012. The mothers' quality of life and self-efficacy were assessed using SF-36 and Sherer's general self efficacy questionnaires before, immediately and 2 months after the training. The training was performed through four 90-minute sessions in 4 weeks. The data were analyzed using the SPSS statistical software and independent t-test, chi-square, and repeated measure analysis of variance. A significant differences was observed between the intervention and control groups regarding the mean of quality of life across the three study periods [F=59.91, P<0.0001]. A significant difference was also found between the two groups concerning the mean of self efficacy at these times [F=114.11, P<0.0001]. According to the results, providing appropriate training for the mothers of the infants with congenital heart disease increased their quality of life as well as self-efficacy.
ABSTRACT
Hospitalization in neonatal intensive care unit [NICU] leads to a lot of stress and shock to the parents. Nurses, as the primary sources of information, could play an important role in reducing their stress. The aim of this study was to determine the effect of educational program on the premature infants' parental stress in NICU. This double-blind randomized controlled trial study with a pre-and post-test and follow up design was conducted from February 2013 to March 2014. Sixty parents in Hazrat Zainab hospital affiliated to Shiraz University of Medical Sciences were randomly allocated into the intervention [received educational program] and control groups [received routine care]. The valid and reliable "Parental Stressor Scale: Neonatal Intensive Care Unit [PSS: NICU]" was used to measure the parental stress. In the intervention group, information about general condition of the baby, the equipment and unit's environment, spouse support, and problem solving strategies were given. The data were collected the second day after admission, fifth day after admission, and a week after the intervention. The data were analyzed in SPSS [Version 14], using t-test and repeated measures analysis of variance. In the second day after admission, the mean score of stress in premature infants' mothers and fathers in the intervention group were 94.79 +/- 14.28 and 76.77 +/- 16.39, respectively. In the control group, it was 94.48 +/- 20.03 and 92.30 +/- 21.95 for mothers and fathers. After the intervention in the fifth day of admission, a significant difference was observed between the two groups concerning the premature infants' maternal [t=-5. 23, P<0.0001] and paternal [t=-6.17, P<0.0001] stress. Moreover, a week after the intervention, the stress mean scores were [in the intervention group: for mothers=59.72 +/- 13.55 and for fathers=61.22 +/- 18.00], and [in the control group: for mothers=86.75 +/- 12.12 and fathers=84.70 +/- 18.46]. Moreover, a significant difference was shown between the two groups concerning the premature infants' maternal [F=23.05, P<0.0001] and paternal [F=17.35, P<0.0001] stress mean scores during the three study periods. The results of this study showed that parents' educational program can reduce their stress and they can spend their energy to support and care for their baby instead of coping with stress