ABSTRACT
Objective To evaluate the differentiating diagnosis value of coincidence SPECT/CT fusion imaging used in the soli-tary“hotspots”in the whole body bone imaging.Methods Fifty patients with malignancy were selected to have examination.the sensitivity,specificity and accuracy of these imaging methods were calculated by contrasting the pathology examination,CT and MRI examination,more than 6 months follow-up results between the cases.Results The sensitivity,specificity and accuracy of SPECT imaging were 94%,23%,and 63%,respectively,and that of CT were 47%,87%,66%;the sensitivity,specificity and accu-racy of SPECT/CT were 95%,80%,88%,respectively.The specificity and accuracy of SPECT/CT was significantly higher than SPECT(P<0.05)and its sensitivity and accuracy was higher than that of CT(P<0.05).Conclusion Coincidence SPECT/CT hy-brid imaging could raise the sensitivity,specificity and accuracy of diagnosis of solitary“hotspot”in whole bone imaging,which is of high clinical application value.