ABSTRACT
Sarcoidosis is a chronic granulomatous disease of undeterminable aetiology affecting multiple organs. Bony affection is rare, and often difficult to be diagnosed. Through observation of two cases we tried to characterize clinically the osseous lesions and their effect on prognosis by clarifing the interest of osseous scintiscanning in the early detection of these lesions. Observation 1: A female patient aged 44 years, treated from pulmonary sarcoidosis since 6 years. Diagnosis of bony sarcoidosis of the right radius has been suspected depending on the clinical picture, radiological and isotopic scanning features. Bone scanning also spotted other lesions in the controlateral left wrist. Observationn 2: A female patient aged 56 years, in whom a neurological sarcoidosis with a cranial bone affection has been diagnosed by a direct osseous scintigraphic bone biopsy. Discussion: Osseous sarcoidosis affection predominates at the hands and feet bones. Often starting, with phalengeal pain tumification. In our observation, bony scintigraphy has been individualised by accurate precession of different diseased sites if compared with standard x. ray images and also by discovering asymptomatic lesions. This exploration also contributes in evaluation of the disease similar to the biological assessment, ensuring early mangement of infammatory attacks