ABSTRACT
BACKGROUND: The eating habits of Jeju Island natives are quite different from those of the mainland people because of geographic isolation. Diet is a main factor affecting gallstone disease. We investigated the prevalence of gallstone disease in both Jeju Island natives and migrants and studied the risk factors affecting gallstone disease in the Jeju Island people. METHODS: A total of 20,763 subjects who underwent medical checkups at the Health Promotion Center of Jeju National University Hospital in Korea from January 2003 to December 2015 were enrolled in the study. Ultrasonography was used to determine the presence of gallbladder stones. Body mass index and biochemical parameters, including liver function test results, lipid profiles, and fasting blood glucose levels, were verified, and data on age, birthplace, and sex were collected from medical records. Univariate and multivariate analyses were performed to identify risk factors affecting gallstone disease. RESULTS: The prevalence of gallstone disease in the Jeju Island people was 4.0%: Jeju Island natives, 3.8% and migrants, 4.4% (P=0.047). After multivariate logistic regression analysis, the independent risk factors were older age, Jeju migrants, higher fasting blood glucose and alanine aminotransferase levels, and lower high-density lipoprotein cholesterol levels. CONCLUSION: The prevalence of gallstone disease was significantly lower in natives than in migrants from Jeju Island. Older age, Jeju migrants, higher fasting blood glucose and alanine aminotransferase levels, and lower high-density lipoprotein cholesterol levels contributed to gallstone disease prevalence in the Jeju Island people.
Subject(s)
Humans , Alanine Transaminase , Alcohol Drinking , Blood Glucose , Body Mass Index , Cholesterol , Diet , Dietary Carbohydrates , Eating , Fasting , Gallbladder , Gallstones , Health Promotion , Korea , Lipoproteins , Liver Function Tests , Logistic Models , Medical Records , Multivariate Analysis , Population Groups , Prevalence , Risk Factors , Transients and Migrants , UltrasonographyABSTRACT
OBJECTIVES: The relationship between subclinical hypothyroidism and cardiovascular disease has not yet been clearly defined. This study will investigate whether or not there is a difference in the prevalence of subclinical hypothyroidism in menopausal women with respect to cardiovascular risk factors, and will furthermore analyze the relationship between cardiovascular diseases and subclinical hypothyroidism, in order to establish a foundation for subclinical hypothyroidism research. METHODS: The study subjects consisted of 713 post-menopausal women, who visited the hospital for a health check-up in 2006-2010. They were divided into a subclinical hypothyroidism group and a normal group. This study analyzed the difference in blood pressure, serum lipid, body mass index (BMI) and blood glucose level between the two groups. The data was analyzed using a two-sample t-test. RESULTS: The prevalence of subclinical hypothyroidism for menopausal women was 6.7%. The results showed no significant differences between the normal and subclinical hypothyroidism patient groups, in regards to blood pressure, BMI, and blood glucose levels (P > 0.05). However the triglyceride of serum lipid was significantly higher in the subclinical hypothyroidism group (P = 0.003). CONCLUSION: It has been confirmed that the triglyceride of the subclinical hypothyroidism group was higher than that of the normal group, and so serum lipid maintenance and caution towards cardiovascular disease is necessary for the subclinical hypothyroidism group.
Subject(s)
Female , Humans , Middle Aged , Blood Glucose , Blood Pressure , Body Mass Index , Cardiovascular Diseases , Hypothyroidism , Postmenopause , Prevalence , Risk Factors , TriglyceridesABSTRACT
A renal infarct is too rare a disease for early diagnosis and treatment. Furthermore, it presents nonspecific symptoms in many patients. Cardiac diseases such as valvular heart disease and arterial fibrillation are the most common causes of renal infarct. Vascular disease such as renal artery dissection or aortic dissection, trauma, inflammation, vasculitis, malignancy and antiphospholipid syndrome have been also known as possible causes of renal infarct. In acute pancreatitis, adjacent vessels can be involved, and were reported to induce splenic infarction, portal vein thrombosis and superior mesenteric vein thrombosis etc. However, the renal infarct from renal artery involvement in acute pancreatitis has not yet been reported. In our case, a 46 year old male patient had an abdominal trauma due to an in-car accident to develop a rupture of pancreatic tail. The progression of acute pancreatitis caused the inflammation of left renal artery, leading to renal artery obstruction. We report a case of renal infarct developed in acute pancreatitis.
Subject(s)
Humans , Male , Antiphospholipid Syndrome , Early Diagnosis , Heart Diseases , Heart Valve Diseases , Inflammation , Mesenteric Veins , Pancreatitis , Portal Vein , Renal Artery , Renal Artery Obstruction , Rupture , Splenic Infarction , Thrombosis , Vascular Diseases , VasculitisABSTRACT
Although a large number of studies have reported the causes of the exacerbation of ulcerative colitis (UC), the effect of influenza vaccination on the relapse of UC has not been reported. We experienced a case of prompt exacerbation of quiescent UC due to influenza vaccination. A 39-year-old woman was diagnosed as UC 4-years ago and was well controlled with oral mesalazine. She experienced abdominal pain and frequent bowel movements with hematochezia 3 days after the vaccination. On admission, laboratory findings showed elevated erythrocyte sedimentation rate and C-reactive protein. Sigmoidoscopy showed marked edematous mucosa on rectum and sigmoid colon with fine ulceration and spontaneous bleeding. She recovered from the exacerbation of UC after steroid treatment. Vaccination should be administered to the patients with inflammatory bowel disease with the caution of its possible side effects.
Subject(s)
Adult , Female , Humans , Blood Sedimentation , C-Reactive Protein/analysis , Colitis, Ulcerative/diagnosis , Influenza Vaccines/administration & dosage , Recurrence , Sigmoidoscopy , Tomography, X-Ray ComputedABSTRACT
Foreign bodies in the upper aerodigestive tract are one of the most frequently encountered accidental cases in the otolaryngological fields, and may cause severe complications such as esophageal ulceration, esophageal perforation, periesophagitis, tracheoesophageal fistula, mediastinitis, pneumothorax and pyothorax. Therefore, speedy diagnosis and early intervention is needed to reduce morbidity and mortality. Recently, we experienced a rare case of esophageal foreign body which caused unilateral vocal cord paralysis. We report this case with a review of literature.
Subject(s)
Diagnosis , Early Intervention, Educational , Empyema, Pleural , Esophageal Perforation , Foreign Bodies , Mediastinitis , Mortality , Pneumothorax , Tracheoesophageal Fistula , Ulcer , Vocal Cord ParalysisABSTRACT
Kaposi's sarcoma is one of the important features of acquired immunodeficiency syndrome (AIDS) patients, renal transplanted patients, young African men, and elderly Ashkenazi Jews. It is well recognized as the most common malignancy asssociated with AIDS and there is also an increased incidence among patients with iatrogenic immunosuppression secondary to renal transplantation. However, a few cases of Kaposi's sarcoma in immunosuppressed patients not related to the renal trans-plantation had been reported. In this study, we present a case of Kaposi's sarcoma involving the oropharynx and the skin of a patient who was not associated with AIDS nor treated with special immunosuppressive agents for renal transplantation.
Subject(s)
Aged , Humans , Male , Acquired Immunodeficiency Syndrome , Immunosuppression Therapy , Immunosuppressive Agents , Incidence , Jews , Kidney Transplantation , Oropharynx , Sarcoma, Kaposi , SkinABSTRACT
Benign tumor of the esophagus are rare, and the true incidence rate is unknown. Fibrovascular polyp is the most common intraluminal tumor, although its occurrence is rare. The fibrovascular polyp has been called variously fibroma, fibrolipoma, myxofibroma, polyp, and pedunclated lipoma. The majority of fibrovascular polyps are solitary, but cases of multiple polyps have been reported. Recently the authors have experienced a case of fibrovascular polyp of the upper esophagus, regurgitated into the hypopharyngeal cavity which might been mistaken for laryngo-pharyngeal mass. We report this case with brief review of the literatures.
Subject(s)
Esophagus , Fibroma , Incidence , Lipoma , PolypsABSTRACT
The study was conducted to compare the side effects in myelography of the two non-ionic water-soluble contrastmedias, Iopamidol(Niopam) and Metrizamide(Amipaque). A total of 111 patients were examined, 64 with Iopamidol and47 with Metizamide. Side effects consisted of headache, nausea, vomiting, dizziness, urinary difficulty, muscularpain, seizure, neurobehavioral distrubance, neurologial sign change, vital sign change and etc. The common sideeffects were headache, nausea, vomiting and dizziness in order of frequency. Most of the side effcts were subsidedwithin 24 hours following meylography. Iopamidol myelography caused fewer and milder side effects than Metrizamidestudy. The side effects were more commonly observed in cervial, thoracic or total myelography than in lumbarmyelography with either lopamidol or Metrizamide. There was no significant correlation between incidence of theside effects and premedication with phenobarbital or valium injection before myelography and CSF sampling duringthe procedure.