ABSTRACT
The plasma levels of D-dimer can be used as a marker of fibrin formation and degradation. Plasma D-dimer levels in the febrile phase of 6 patients with typhoid fever and in the afebrile convalescent phase of 4 of them were measured. D-dimer levels were high in the febrile phase of all 6 patients and within normal range in the afebrile convalescent phase of all 4 patients. Our results indicate that thrombus formation and fibrinolysis may occur in the febrile phase of patients with typhoid fever.
Subject(s)
Adolescent , Adult , Female , Fever/blood , Fibrin/metabolism , Fibrin Fibrinogen Degradation Products/metabolism , Humans , Male , Thrombosis/blood , Typhoid Fever/bloodABSTRACT
We report a case of Weil's disease manifesting elevation of plasma D-dimer in the acute phase. Later, in the convalescent phase after treatment, the plasma levels of D-dimer returned to normal. Plasma D-dimer can be used as a marker of fibrin formation and degradation. Based on our observations, we conjecture that fibrin formation and fibrinolysis may occur in the acute phase of Weil's disease.
Subject(s)
Acute Disease , Adult , Biomarkers/blood , Fibrin Fibrinogen Degradation Products/analysis , Humans , Male , Weil Disease/bloodABSTRACT
An elderly bisexual male AIDS patient, whose CD4 cell count was 128/mm3 and HIV-RNA was 3.0x10(5) copies/ml, was admitted because of amebic liver abscess and poor nutritional condition. He was treated with daily doses of 1,500 mg of metronidazole for 14 days for amebic liver abscess and with anti-HIV drugs; good therapeutic results were observed. Our study indicates that amebic liver abscess is easily treated by appropriate administration of metronidazole even in an old AIDS patient receiving anti-HIV drugs with low CD4 cell counts and high HIV-RNA values.
Subject(s)
Acquired Immunodeficiency Syndrome/complications , Aged , Anti-HIV Agents/therapeutic use , Anti-Infective Agents/therapeutic use , Humans , Liver Abscess, Amebic/complications , Male , Metronidazole/therapeutic useABSTRACT
In Echinococcus multilocularis metacestodes obtained from the peritoneal cavity of an experimentally infected jird, cellular accumulations were found not only on the inner surfaces of germinal layers but also on the outer surfaces of brood capsules. These cellular accumulations are believed to represent at incipient form of the brood capsule. It has been thought that brood capsules are produced by the germinal layer, but we speculate that the brood capsule itself, as well as the germinal layer, may have the potential to produce new brood capsules.