An overview on the current available treatment for COVID-19 and the impact of antibiotic administration during the pandemic

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has caused several problems in healthcare systems around the world, as to date, there is no effective and specific treatment against all forms of COVID-19. Currently, drugs with therapeutic potential are being tested, including antiviral, anti-inflammatory, anti-malarial, immunotherapy, and antibiotics. Although antibiotics have no direct effect on viral infections, they are often used against secondary bacterial infections, or even as empiric treatment to reduce viral load, infection, and replication of coronaviruses. However, there are many concerns about this therapeutic approach as it may accelerate and/or increase the long-term rates of antimicrobial resistance (AMR). We focused this overview on exploring candidate drugs for COVID-19 therapy, including antibiotics, considering the lack of specific treatment and that it is unclear whether the widespread use of antibiotics in the treatment of COVID-19 has implications for the emergence and transmission of multidrug-resistant bacteria.

Pacientes difíciles en dermatología / Difficult patients in dermatology

La prevalencia de los trastornos psicosomáticos, dentro de los pacientes dermatológicos es muy alta, pero con frecuencia no se logra una terapéutica adecuada, debido a las severas dificultades en el abordaje, diagnóstico y tratamiento que los mismos representan. Patologías psiquiátricas y psicológicas, pueden desempeñar diferentes funciones en el mecanismo patogénico de varias enfermedades, que se manifiestan en la piel. La base del diagnóstico y del tratamiento, reside en poder diferenciar entre los trastornos de la piel asociados con enfermedades psiquiátricas y las de carácter puramente psiquiátrico pero que se expresan en la piel. Los dermatólogos y psiquiatras deben ser conscientes de estas patologías y trabajar juntos en equipo, para resolver estos difíciles casos.

The prevalence of psychosomatic disorders in dermatology patients is very high, but often adequate treatment is not achieved due to the severe difficulties in addressing diagnosis and treatment thereof. Psychiatric and psychological factors may play different roles in the pathogenic mechanism of some skin diseases. The basis of diagnosis and treatment is the differentiation between skins disorders associated with mental illness and psychiatric purely character. Dermatologists and psychiatrists should be aware of this condition and work together as a team to solve these difficult cases.