Experimental resin-based dual-cured calcium aluminate and calcium titanate materials for vital pulp therapy

Abstract: This paper evaluates the physicochemical and biological properties of experimental resin-based dual-cured calcium aluminate (CA) and calcium titanate (CTi) materials for vital pulp therapy (VPT). The experimental dual-cured materials were obtained as two pastes: a) Bis-EMA 10, PEG 400, DHEPT, EDAB, camphorquinone, and butylated hydroxytoluene; and b) fluoride ytterbium, Bis-EMA 10, Bis-EMA 30, benzoyl peroxide, and butylated hydroxytoluene. The materials were divided into six groups based on the added calcium component: MTA (MTA®, Angelus); CLQ (Clinker-Fillapex®, Angelus); CA (calcined at ,1200°C in pastes a and b); CA800 (calcined at 800°C in paste a); CA1200 (calcined at 1,200°C in paste a); and CTi (paste a). The real-time degree of conversion and rate of polymerization (n = 3), diametral tensile strength (n = 10), hydrogen potential (n = 15), calcium ion release (n = 10), water sorption and solubility (n = 10), and cell viability (n = 6) were evaluated. One- and two-way ANOVA and Tukey's post hoc test were used in the analysis of the parametric data, and Kruskal-Wallis and Dunn's multiple tests were used to analyze the nonparametric data (α = 0.05). CLQ, CA800 and CA1200 had the highest diametral tensile strength. The water solubility of MTA was similar to that of CA800, CA1200 and CTi. CA800 and CA1200 resulted in cell viabilities similar to those of MTA and CLQ. The experimental dual-cured CA-based material that calcined at 800°C showed physicochemical and biological properties suitable for VPT, and similar to those of MTA.

Prevotella intermedia: uma breve revisão / Prevotella intermedia: A brief review

Prevotella intermedia é um microrganismo anaeróbio Gram negativo, considerado um dos agentes etiológicos de doenças periodontais. Tendo em vista que o biofilme subgengival é um dos seus principais habitats, qualquer quebra na homeostase do meio pode favorecer seu desenvolvimento e consequente dano aos tecidos atingidos. Diversas pesquisas vêm sendo realizadas a fim de identificar o papel deste microrganismo nas doenças periodontais. Assim, este trabalho teve por objetivo revisar a literatura para coletar informações sobre as características e efeitos de Prevotella intermedia no contexto saúde-doença periodontal. A busca foi realizada nas bases de dados PubMed e Lilacs, bem como através de uma busca aleatória. De um total de 47 artigos incluídos, alguns principais resultados puderam ser destacados: Prevotella intermedia está fortemente associada ao quadro de doenças periodontais e suas características favorecem o acometimento e intensificação de doenças diversas. Além disso, este microrganismo é capaz de produzir pigmentos e uma variedade de enzimas as quais favorecem danos aos tecidos periodontais. Existem várias características que aumentam a patogenicidade e virulência deste microrganismo, como por exemplos a sua cápsula polissacarídica, a presença de enzimas protetoras contra o oxigênio, a presença e produção de proteases, além da estimulação de fatores de crescimento no hospedeiro. Não há consenso na literatura acerca da relação de causa-efeito entre presença de Prevotella intermedia e diabetes. Contudo, este microrganismo parece estar envolvido no quadro de pacientes HIV positivo. Por fim, é importante salientar que Prevotella intermedia pode adquirir resistência a alguns tipos de antibióticos, e, por isso, o seu controle é um desafio à clínica atual...

Prevotella intermedia is a Gram negative anaerobic microorganism, considered one of the etiologic agents of periodontal diseases. Taking into account that the subgingival biofilm is its major habitat, any break of the environment homeostasis may lead to the development of the microorganism and consequent damage to the surrounding tissues. Several researches have been conducted in order to identify the role of this microorganism in the periodontal diseases. Thus, this study aimed to review the literature in an attempt to collect information about the characteristics and effects of Prevotella intermedia in the periodontal healthdisease context. The search was performed in the PubMed and Lilacs databases, as well as under a random search. From a total of 47 included articles, some major results could be drawn: Prevotella intermedia is strongly related to the occurrence of periodontal diseases, and its characteristics lead to the incidence of several diseases. Moreover, this microorganism is able to produce pigments and a variety of enzymes, which potentiate the damage of periodontal tissues. There are several characteristics that increase the pathogenicity and virulence of this microorganism, including the polyssacharidic capsule, the presence of protective enzymes against oxygen, the presence and production of proteases, as well as the stimulation of grow factors in the host. There is no consensus in the literature regarding the cause-effect relationship between the presence of Prevotella intermedia and diabetes. However, this microorganism seems to be involved in the occurrence of HIV-positive people. Lastly, it is worth to mention that Prevotella intermedia may acquire strength to some antibiotic types, and, therefore, its control is a challenge to the current clinic...

Allergic rhinitis and bruxism in children – association andoccurrence

Purpose: The study assessed the occurrence ofallergic rhinitis and bruxism, and the associationbetween these variables from a sample of childrenranging from 1 to 12 years of age in thecity of Santa Maria, RS, Brazil. Study design:This was a retrospective study and data wereanalyzed from 465 records belonging to the PediatricDentistry Clinic at the Federal Universityof Santa Maria from January 1997 to December2008. In a questionnaire applied to the children’sparents, questions about bruxism and allergicrhinitis occurrence were included. The chi-squaretest was used to assess data. Girls made up 51%of the sample and boys 49%. Results: The resultsshowed a 53.1% allergic rhinitis occurrenceand a 23.9% bruxism occurrence. Of the childrenshowing bruxism, 63% also showed allergicrhinitis. Conclusion: Therefore, the associationbetween bruxism and allergic rhinitis was significant.It was concluded that bruxism-bearing childrenare likely to develop allergic rhinitis.

Associação entre o tipo de aleitamento e rinite alérgica: estudo retrospectivo / The association of type of feeding and rhinitis: retrospective study

O objetivo deste trabalho foi o de verificar a possível associação entre tipo de aleitamento e a presença de rinite alérgica (RA). O estudo caracterizou-se por ser retrospectivo, pela análise dos dados secundários de 465 prontuários corretamente preenchidos, de crianças entre 1 e 12 anos de idade, assistidas em instituição pública de Odontopediatria, na cidade de Santa Maria/RS, no período de janeiro de 1997 a dezembro de 2008. Nos prontuários, constavam questões específicas sobre o tipo de aleitamento e ocorrência de alergias. Os dados foram analisados pelo teste do Qui-Quadrado, utilizando o nível de significância de 5%. Houve associação entre o tipo de aleitamento e RA (p<0,01). Os resultados demonstraram que crianças que receberam o benefício do aleitamento materno (aleitamento materno exclusivo e misto) apresentaram menor prevalência de RA, ao contrário das que não o receberam (aleitamento artificial exclusivo). Houve associação entre o tipo de aleitamento e a presença de rinite alérgica.

The purpose of this study was to assess the possible association of types of feeding and allergic rhinitis. The study is characterized by retrospective investigation. Data from 465 correctly completed records of children between 1 and 12 years old, they were assisted in publishing institution of pediatric dentistry in Santa Maria-RS between January 1997 and December 2008. The records had questions about types of feeding and allergic diseases. The data were analyzed by the chi square test and the significance level was 5%. The results showed there is association of types of feeding and allergic rhinitis (p<0.01). Results showed that children with the benefit of breastfeeding showed less allergic rhinitis, in contrast to those who received exclusively artificial feeding. There was an association between types of feeding and allergic rhinitis.