ABSTRACT
Introduction: Rheumatoid arthritis is considered one of the most common, and particularly attacks the joint causing significant individual and community burden, and present with articular as well as extra articular manifestation. Treatment modalities of rheumatoid arthritis have dramatically improved in recent years, significantly decreasing long-term auricular and extra-auricular complications
Aim of the work: this review was aimed to study the pathophysiology, clinical picture, and management of rheumatoid arthritis, with focus on the newer modalities.
Methodology: We conducted this review using a comprehensive search of MEDLINE, PubMed, and EMBASE, January 1985, through February 2017. The following search terms were used: rheumatoid arthritis, chronic inflammatory disorders, genetic of rheumatoid arthritis, management of rheumatoid arthritis, DMARD, biological agents
Conclusion: The newer modality of treatment must include disease-modifying antirheumatic drug [DMARDs] which must be started as early as possible. Combining DMARDs with corticosteroids will result in significantly better outcomes than monotherapy with any DMARD, and decrease long term morbidity associated with this condition
ABSTRACT
Background: Thalassemia major has become a public health problem worldwide, mainly in developing and poor countries, while the role of educating the family and community has not been considered enough in patients' care
Purpose: This study was done to examine the impact of partnership care model on mental health of patients with beta-thalassemia major
Materials and Methods: This experimental study, with pretest and posttest design, was performed on patients with beta-thalassemia major in Jeddah city. 40 patients with beta-thalassemia major were assigned randomly into two groups of intervention [20 patients] and control [n=20] groups. Mental health of the participants was measured using the standard questionnaire before and after intervention in both groups. The intervention was applied to the intervention group for 6 months, based on the partnership care model
Results: There were significant differences between the scores of mental health and its subscales between the two groups after the intervention [P< 0.05]
Conclusions: The findings of the study revealed the efficacy and usefulness of partnership care model on mental health of patients with beta-thalassemia major; thus, implementation of this model is suggested for the improvement of mental health of patients with beta-thalassemia major