ABSTRACT
An adult, wild newly captured female rock hyrax was presented to the Egyptian Desert Research Center with a history of anorexia and severe emaciation. Medical investigation showed evidence of abdominal pain, and gross haematuria, no intestinal or blood parasite investigated. The rock hyrax later died and postmortem and clinical examinations revealed the presence of bloody urine in the urinary bladder and sever congestion of the kidneys. Histopathological examination of the renal cortex revealed diffuse glomerular damage which as severe congestion of the glomerular capillaries, and the intertubular blood vessels with mild proliferation of mesangial cells without infiltration of neutrophiles. The renal medulla showed Severe vacuolization of tubular cells in injured tubular epithelium with signs of acute tubular damage [ATD]. Noninfectious Glomerular and tubular damage may be related to the short term vigorous exercise exerted by the animal before capture