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Article in English | IMSEAR | ID: sea-151472

ABSTRACT

This paper comprises two series of complexes which showed different modes of coordination. The fist series involved an N,N’,N”-donor Schiff base ligand from the reaction of 2-acetylpridine as carbonyl compound with N,N’-dimethylethylenediamine (L1), the second series involved N,N’,O-donor Schiff base from the condensation reaction of 2-hydroxyacetophenone (ketone) as carbonyl compound with N,N’-dimethylethylenediamine (L2). The ligands and complexes were characterized by using melting point, elemental analysis, FT-IR, NMR, and UV/Visible spectroscopy. The complexes showed very low cytotoxicity towards MCF-7 breast cancer cell line. They also showed moderate zone inhibition against Gram positive bacterium Methicillin-resistant Staphylococcus aureus, Acinetobacter baumannii and Pseudomonas aeruginosa. No antimicrobial activity observed with Klebsiella pneumonia.

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