Liver functions changes in acute diarrhea in children

Diarrhea is considered to be one of the most common causes of morbidity and mortality among infants and children in developing countries. The present study was done to evaluate the incidence of hepatic affection or the occurrence of abnormal liver functions in infants and children presented with acute diarrhea with different degrees of dehydration. The study demonstrated that total number of patients with liver function impairment were [22.5% of cases]. All of them had elevated AST, either single elevation in 60% of cases with impaired liver function or combined AST and ALT elevation in 40% of cases with impaired liver function. The mean value of AST was 95 u /1 +/- 75.4, where mean value of ALT was 124 u/l +/- 8-5.8

Plasty transposition flaps a new technique in closure of skin defects after lumbosacral meningomylocele resection in pediatrics

Different closure techniques are available after lumbosacral meningomylocele [MMC] resection for large defects reconstruction, but wound healing and tension-free closure in the midline remain major considerations. In this study we use Z plasty technique in closure of MMC defects>5 cm. Twenty newborns with large lumbosacral MMC were enrolled in this study. The mean age was 57.45 +/- 59.8 days. Complete healing of the skin occurred within two weeks in 14 patients [70%]. Superficial wound infection was seen in four patients [20%]. Necroses of the edges of the flap were showed in two patients [10%]. No mortality or complete wound dehiscence were observed in this study. Almost skin wounds healed without any major complications