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1.
Arch. cardiol. Méx ; 89(1): 5-11, Jan.-Mar. 2019. tab, graf
Article in English | LILACS | ID: biblio-1038470

ABSTRACT

Abstract Introduction: Carotid disease, measured as carotid intima-media thickness (CIMT) and carotid plaque (CP), is associated with major adverse cardiac and cerebrovascular events (MACCE) in people without the previous atherosclerotic disease; however, there are few published data in patients undergoing coronary angiography. The aim of the study is to determinate if the carotid disease is associated with MACCE after coronary angiography. Methods: A total of 390 consecutive patients underwent coronary angiography after exercise echocardiography and carotid ultrasonography between 2002 and 2013. MACCE was defined as stroke, myocardial infarction due to atherosclerosis progression or death due to a stroke or cardiac event. Results: Two patients were lost (0.5%). During a mean follow-up of 6.0 years (standard deviation of 2.9), 52 patients (13.4%) suffered MACCE. 1, 5, and 10 years, event-free survival was 96.4% (1.0), 88.7% (1.7), and 81.4% (2.8), respectively. Event rates at 10 years were higher in the CP group (23.2% vs. 10.2%, p = 0.013) and in the CIMT > 0.9 mm group (25.9% vs. 13.3%, p = 0.023). Multivariate analysis showed smoking habit (hazard ratio [HR] 2.51, 95% confidence interval [CI] 1.36-4.62, p = 0.003), glomerular filtration rate (HR 0.98, 95% CI 0.98-0.99), aortic stenosis (HR 2.99, 95% CI 1.24-7.21, p = 0.014), incomplete/no coronary revascularization (HR 1.97, 95% CI 1.06-3.67, p = 0.033), insulin treatment (HR 2.63, 95% CI 1.30-5.31, p = 0.006), and CP (HR 2.36, 95% CI 1.02-5.44, p = 0.044) as predictors of MACCE. Conclusions: CP is an independent predictor of MACCE in patients undergoing coronary angiography.


Resumen La enfermedad carotídea, definida como grosor de íntima media (GIMC) y placa (PC), se asocia con eventos adversos cardiacos y cerebrovasculares (EACC) en sujetos sin aterosclerosis previa; sin embargo hay pocos datos en pacientes sometidos a coronariografía. El objetivo del estudio es determinar si la enfermedad carotídea se asocia a EACC en pacientes remitidos a coronariografía Métodos: Entre 2002 y 2013 390 pacientes fueron sometidos a coronariografía tras ecocardiograma de esfuerzo y ecografía carotídea. Se definió EACC como accidente cerebrovascular, infarto de miocardio por progresión aterosclerótica o muerte por accidente cerebrovascular o causa cardiaca. Resultados: Durante un seguimiento medio de 6 años (desviación estándar 2, 9) se registraron 2 pérdidas y 52 eventos (13,4%). La supervivencia media libre de eventos a uno, cinco y diez años fue 96.4% (1.0), 88.7% (1.7) y 81.4% (2.8). Hubo mayor número de eventos a 10 años en el grupo de PC (23.2% frente 10.2%, p = 0.013) y GIMC > 0.9 mm (25,9% frente 13.3%, p = 0.023). En el análisis multivariado los predictores de EACC fueron tabaquismo (hazard ratio [HR] 2.51, intervalo de confianza [IC] al 95% 1.36-4.62, p = 0.003), filtrado glomerular renal (HR 0.98 IC95% 0.98-0.99), estenosis aórtica (HR 2.99, IC 95% 1.24-7.21, p = 0.014), revascularización incompleta/no revascularización (HR 1.97, IC 95% 1.06-3.67, p = 0.033), tratamiento con insulina (HR 2.63, IC 95% 1.30-5.31, p = 0.006) y PC (HR 2.36, 95%CI 1.02-5.44, p = 0.044). Conclusiones: La PC es un predictor independiente de EACC en pacientes sometidos a coronariografía.


Subject(s)
Humans , Male , Female , Adult , Middle Aged , Aged , Aged, 80 and over , Carotid Artery Diseases/complications , Coronary Angiography , Stroke/etiology , Plaque, Atherosclerotic/complications , Myocardial Infarction/etiology , Carotid Artery Diseases/diagnosis , Survival Analysis , Retrospective Studies , Risk Factors , Follow-Up Studies , Disease Progression , Stroke/diagnosis , Stroke/mortality , Myocardial Infarction/diagnosis
2.
Rev. cuba. enferm ; 22(3)jul.-sept. 2006. tab
Article in Spanish | LILACS, CUMED | ID: lil-465318

ABSTRACT

Se realizó un estudio descriptivo retrospectivo que estuvo relacionado con la aplicación de la electroacupuntura en pacientes sometidas a legrados diagnóstico, con el objetivo de evaluar su efectividad. Se aplicó analgesia mediante la electroacupuntura a 201 pacientes que presentaron riesgos de contraindicaciones a la anestesia general y algunas que se decidieron a participar en el estudio de forma voluntaria. Se analizaron las variables: edad, riesgo anestésico, complicaciones transoperatorias, valoración del dolor, tipo de procedimiento realizado y evaluación del tratamiento. Se registró que el 63,1 por ciento de los casos tenían entre 41-60 años de edad, el 73,6 por ciento de los pacientes presentaron riesgo anestésico y hubo una efectividad de la analgesia mediante la electroacupuntura para el 96,1 por ciento. No refirieron dolor durante el transoperatorio el 85 por ciento de los pacientes y solo el 9,9 por ciento presentó complicaciones, predominando la hipertensión arterial. El 75,6 por ciento refirió que el método de analgesia mediante la electroacupuntura fue una alternativa muy buena(AU)


A descriptive retrospective study related to the application of electroacupuncture in female patients undergoing diagnostic curettages was conducted in order to evaluate its efectiveness. Electroacupuncture analgesia was administered to 201 patients that presented risks of contraindications to general anesthesia and to some of them that decided to participate in the study as volunteers. The following variables were analyzed: age, anaesthetic risk, transoperative complications, assessment of pain, type of procedure carried out and treatment evaluation. It was observed that 63.1 percent of the cases were between 41 and 60 years old, and that 73.6 percent of the patients presented anesthesic risk. Electroacupuncture analgesia showed an effectivity of 96.1 percent. 85 percent of the patients did not refer pain in the transoperative, and only 9.9 percent had complications, with predominance of arterial hypertension. 75.6 percent considered electroacupuncture analgesia as a good alternative(AU)


Subject(s)
Humans , Electroacupuncture/adverse effects , Curettage/methods , Analgesia/adverse effects , Epidemiology, Descriptive , Retrospective Studies
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