Left pulmonary artery agenesis with pulmonary hypoplasia in an elderly patient: a rare case report.

Proximal interruption of the unilateral pulmonary artery is a rare congenital anomaly, which is often associated with other cardiovascular abnormalities. It is usually diagnosed in children but rarely discovered in adulthood as an isolated phenomenon, occurring more frequently on the right side and is often associated with a contralateral aortic arch. We are presenting a rare case of a sixty year old male who was diagnosed with left lung hypoplasia due to proximal interruption of left pulmonary artery with left sided aortic arch without any associated cardiovascular anomalies.

Pulmonary Lymphangitis Carcinomatosis In Primary Oesophagogastric Carcinoma.

Pulmonary Lymphangitis carcinomatosis is an unusual metastatic manifestation of Oesophagogastric carcinoma and it occurs due to diffuse spread of the tumour to the pulmonary lymphatic system. We described a case of a 28 year old woman, presenting with gradually progressive dyspnoea and cough where results of Chest X-ray and HRCT thorax were consistent with features of Lymphangitis carcinomatosis. Upper GI endoscopic evaluation showed a tumour originating from oesophagogastric junction and extending to cardia of stomach. Biopsy from tumour revealed adenocarcinoma. As there is no definitive therapy to this condition, patient was managed conservatively only to succumb few days after hospitalisation.

Standardization of a dot blot immunoassay for antigen detection in cases of pulmonary tuberculosis & its evaluation with respect to the conventional techniques.

A simple dot (blot) ELISA test for detecting tubercular antigen in sputum samples of patients of pulmonary tuberculosis has been standardized using nitrocellulose paper. The sensitivity of the assay is 20 ng/ml. The cut-off value was 80 ng/ml. Of the 1042 patients in the study group, the percentage positivity by smear and culture was 54.51 and 57.93 per cent respectively; 68.7 per cent of the ELISA positives were confirmed by smear. The dot blot ELISA could be used as a rapid and specific test as it not only picked up 88.88 per cent of the smear positive, culture positive cases but also 81.89 per cent of the smear negative, culture positive cases. If the results of smear and dot blot ELISA are combined, 91.08 per cent of the culture positive cases were picked up as positive. If such a noninvasive test is commercialized and used in conjunction with smear, the pick up rate of tuberculosis cases will improve considerably.