ABSTRACT
Aim: Most of the studies were on adult ossicles. In this present work, the aim is to study the morphometry of the ear ossicles in the human fetuses and use of the study in medical applications. Materials and Methods: This study is performed on 100 sets of middle ear ossicles, each set consisting of Malleus, Incus and Stapes, which were taken from 50 fetal cadavers left and right sides of both. Result: The morphometric data of malleus and incus in their length are 5.21mm and 4.85mm, the height of the stapes is 2.52mm. The indices of malleus, incus and stapes are 51.28, 67.54 and 88.12mm. Conclusion: The study of morphometry in the ear ossicles of the human fetal cadavers can be useful for prosthetic surgical reconstruction.
ABSTRACT
Aim: To study the morphological variation, if any, of the ear ossicles in the human fetuses and use of the study in medical applications. Materials and Methods: This study was performed on 100 sets of middle ear ossicles, each set consisting of Malleus, Incus and Stapes, which were taken from 50 fetal cadavers on either side. Observations: All the three ossicles showed variations in their morphology and more so in the stapes. Discussion: There are few studies in the literature on individual differences in these ossicles and these studies were on either adult or different species. Conclusion: the ear ossicles of the destitute human fetuses can be used as homografts to replace eroded adult middle ear ossicles.
ABSTRACT
Introduction: ION receives proprioceptive impulses from spino-olivary tract and conveys the fibers to the cerebellum through olivo-cerebellar tract. There is paucity of data in human olivary complex, hence the present study is done. Materials and Methods: Study was conducted with 15 adult brains and 25 fetuses of different gestations were perfused with 10% formalin and processed for histological examination. Obeservations: Rounded cells have been seen infiltrating the entire field. at 16 weeks of gestation. Segregation of neurons into principal, medial, and dorsal accessory olivary nuclei at 20 wks gestation. Discussion: Neuron differentiation into oval, round, multipolar types has begun at 40 wks gestation. Neurons in the olivary subdivisions are grouped in separate clusters as per Ramon y Cajal,1909; Scheibel and Scheibel, 1955, Bowman and King, 1973. Multipolar neurons dominated in adult inferior olivary nucleus. Conclusion: The greater development of neurons is a consequence of finer regulation of various movements of hands and finger associated with movement of head and eyes.
ABSTRACT
Sexual dimorphism in human corpus callosum is controversial, and only a limited number of studies have been done on foetuses. Corpus callosum of 50 foetal brains, 25 male and 24 female were studied however, one foetus with undifferentiated sex, was excluded from the present study. The crown rump length (CRL) and the brain weight of these foetuses ranged from 5 to 39 cm and 10 to 550 gm. Brain was divided into two equal halves by median section after fixation. The length of the corpus callosum, pre-callosal and post-callosal lengths, were measured on the medial aspect of each cerebral hemisphere. The thickness of splenium was measured in the sagittal section. The brain weight increased with increase in the CRL length in all the foetuses. The average length of the corpus callosum was more in males than in females. The z test value was 1.3871, which is not significant. The thickness of splenium was more in females than male. The z test value was 2.28, which is highly significant. Sex difference was not observed in any of the other parameters.
ABSTRACT
Polycystic kidney disease is one of the life-threatening inherited disorder summated by the development of bilateral or unilateral renal cysts that might lead to renal failure in due course of time. This disorder affects 1 in 1000 live births. A still born male human foetus of 31 weeks gestation was brought from one of the private nursing homes by post graduate students for study of foetal anomalies as part of their project work. During dissection of the foetus, the kidneys were found to be of 8 cms in length and 5.5 cms in width which were almost of the adult size. The kidneys were subjected to histological examination. Microscopic examination revealed scanty cortical areas with glomeruli and proximal convoluted tubules with large cystic cavities at the juxta cortical regions.