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Arq. bras. endocrinol. metab ; 54(4): 369-374, jun. 2010. graf, tab
Article in Portuguese | LILACS | ID: lil-550706

ABSTRACT

As alterações metabólicas decorrentes do diabetes melito tipo 1 (DM1) podem prejudicar o crescimento e o desenvolvimento. OBJETIVO: Avaliar a estatura final de pacientes com DM1 e a interferência da doença no crescimento. PACIENTES E MÉTODOS: A estatura final de 58 pacientes com DM1 foi avaliada em relação aos dados antropométricos e controle metabólico. RESULTADOS: A idade média foi de 26,4 anos (15,0-51,0) e a duração da doença, de 9,6 anos (1,4-25,0). A estatura final foi 165,1 cm (149,3-183,0) e o z-escore da estatura final foi igual a 0,09 (-1,76-2,85). Num subgrupo (n = 34), foi possível avaliar o controle glicêmico durante a fase de crescimento estatural. A média de hemoglobina glicosilada foi 12,2 por cento (6,8-24,1) e as correlações entre dados antropométricos e controle glicêmico não foram estatisticamente significantes (p > 0,05). CONCLUSÃO: Não houve interferência do DM1 na estatura final, apesar do controle glicêmico inadequado.


Metabolic changes resulting from type 1 diabetes mellitus (DM1) may put growth and development at risk. OBJECTIVE: To evaluate the final stature of DM1 patients and the interference of DM1 in growth. SUBJECTS AND METHODS: The final height reached by 58 DM1 patients was evaluated according to anthropometric data and metabolic control. RESULTS: Mean age was 26.4 years (15.0-51.0) and the duration of disease was of 9.6 years (1.4-25.0). Final stature was 165.1 cm (149.3-183.0) and the z-score for height was 0.09 (-1.76-2.85). In a subgroup (n = 34), it was possible to evaluate the effect of metabolic control on growth. Mean glycosylated hemoglobin was 12.2 percent (6.8-24.1) and the correlation between anthropometric data and glucose control was not considered statistically significant (p > 0.05). CONCLUSION: We conclude that DM1 had no effect on the final stature, to the detriment of a poor metabolic control.


Subject(s)
Adolescent , Adult , Female , Humans , Male , Middle Aged , Young Adult , Body Height/physiology , Diabetes Mellitus, Type 1/complications , Growth Disorders/diagnosis , Diabetes Mellitus, Type 1/blood , Glycated Hemoglobin/metabolism , Outsourced Services , Statistics, Nonparametric , Time Factors
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