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1.
Indian J Physiol Pharmacol ; 2019 Apr; 2: 155-159
Article | IMSEAR | ID: sea-198932

ABSTRACT

Background: Poor sleep can challenge normal glucose homeostasis in type-2 diabetics and usually isunder-diagnosed. The study aimed to assess subjective sleep quality and duration among diabetics.Methods: A cross-sectional study was carried out in a tertiary care center in Visakhapatnam during theperiod from January 2018 to April 2018. A total of 444 type-2 diabetics, aged t18 years were recruited.Subjective sleep quality was assessed using Pittsburgh Sleep Quality Index (PSQI) with cut off value >5indicating poor sleep quality. Participant’s demographic features, co-morbid conditions, body mass indexand glycemic profile were collected.Results: Subjective sleep quality was poor in 54.95% of diabetic patients. The mean global PSQI score was6.08±2.84. Pain was the highest reported sleep-related problem followed by nocturia. The Multivariate LogisticRegression analysis showed that females, physical inactivity, duration of DM >5 years, co-morbid conditionsand poor glycemic control had significant association with subjective poor sleep quality in diabetics.Conclusion: Nearly half of the diabetic patients reported poor subjective quality of sleep with poor glycemiccontrol.

2.
Indian J Physiol Pharmacol ; 2014 Oct-Dec ; 58 (4) : 365-370
Article in English | IMSEAR | ID: sea-156223

ABSTRACT

Physical inactivity is an important risk factor for cardiovascular mortality and morbidity. Regular exercise is known to improve health and maintain physical fitness. The heart rate response to exercise reflects autonomic control of heart and has shown to predict cardiovascular prognosis. Decreased heart rate variability (HRV) is known as a risk factor for cardiovascular mortality. The objective of this study was to study the effect of exercise on cardiac autonomic activity. Thirty two healthy adult men in the age group of 18-25 years with normal body mass index (BMI) were recruited from different physical fitness centers, who were undergoing regular exercise for past 3 months. Resting ECG was recorded for 5 minutes and analyzed for frequency analysis of HRV. HRV parameters of the subjects were compared with fifty age and BMI matched subjects who were not undergoing any exercise program. Physical activity level of all subjects was assessed by using Global Physical Activity Questionnaire. The exercising (E) subjects were found to have a lesser heart rate (73.27±8.6 vs 74.41±8.59) compared to non-exercising (NE) group, which was not significant. No significant difference was found in frequency domain parameters of HRV between exercising and non-exercising group with LF (47.12±19.17 vs 43.55±16.66), HF (41.03±17.65 vs 46.03±15.89) and LF/HF (1.61±1.16 vs 1.22±0.93) respectively. Physical activity level was significantly different between the two groups (4175±1481.53 vs 1176.4±1103.83, p<0.001). This study showed 3 months of exercise did not have any effect on cardiac autonomic activity despite the difference in physical activity.

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