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Rev. méd. Chile ; 125(2): 161-4, feb. 1997. tab
Article in Spanish | LILACS | ID: lil-194813

ABSTRACT

The sample included 460 controls of a case control study of typhoid fever. The G1m-G2m-G3m most frequent haplotypes were: za,..;g or 1,17;(-);21=0.4493;fn;b or 3;23;5,13=0.2522;f-,..;b or 3;(-);5,13=0.1389; zax;..;g or 1,2,17;(-);21=0.0685;za;..;b or 1,17;(-);5,13=0.0454;za;n;g or 1,17;23;21=0.0207;f;..;g or 3;(-);21=0.0129. The frequencies of Km alleles were 0.2391 and 0.7609 for Km1 and km3 respectively. These frequencies are within those found in Amerindian and Caucasian populations as expected from the origin of the Chilean population. Gm haplotypes did not differ from Hardy-Weinberg equilibrium, while a significant lack of homozygous Km1/km1 was found in Km


Subject(s)
Humans , Male , Female , Adolescent , Typhoid Fever/genetics , Haplotypes/genetics , Immunoglobulin Gm Allotypes/isolation & purification , Immunoglobulin kappa-Chains/genetics , Case-Control Studies
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