Your browser doesn't support javascript.
loading
Show: 20 | 50 | 100
Results 1 - 1 de 1
Filter
Add filters








Year range
1.
Arq. bras. endocrinol. metab ; 52(4): 642-648, jun. 2008. graf, tab
Article in Portuguese | LILACS | ID: lil-485831

ABSTRACT

OBJETIVOS: Por meio da análise de um grupo de pacientes com DM2, temos por objetivos: avaliar por monitoração da glicose subcutânea (MGSG) as excursões pós-prandiais da glicose subcutânea; analisar as correlações da glicose subcutânea e glicemias capilares com a HbA1c e avaliar a eficácia, a segurança e a tolerabilidade da MGSC. MÉTODOS: Foram analisados 40 pacientes com DM2, com HbA1c até 7,3 por cento, em uso de agentes orais e com menos de 10 anos de diagnóstico. Foram submetidos à MGSC por 72 horas, cujos dados foram confrontados com a HbA1c e as glicemias capilares. RESULTADOS: A excursão média da glicose subcutânea do desjejum foi estatisticamente maior que a do jantar (95 por centoIC -24,96 a -1,66). A razão excursão da glicose subcutânea/conteúdo de carboidrato da refeição foi estatisticamente maior no desjejum que nas demais refeições (p = 0,001). Não houve correlação entre as taxas de glicose subcutânea e as glicemias capilares com HbA1c. Não houve complicações com o uso da MGSC. CONCLUSÕES: As excursões de glicose subcutânea predominaram no desjejum. Não se encontrou correlação entre HbA1c e parâmetros de controle glicêmico. A MGSC mostrou-se eficaz, segura e bem tolerada nesse grupo de pacientes.


OBJECTIVES: Through the analysis of a group of type 2 diabetes patients, the aims of this study are: to evaluate through CGMS (continuous glucose monitoring system) the post-prandial subcutaneous glucose excursions; to analyze the correlations between subcutaneous glucose and capillary glycemia with HbA1c and to evaluate the effectiveness, safety and broadmindedness of the CGMS. METHODS: Forty type 2 diabetes patients were analyzed, with HbA1c until 7.3 percent, in use of oral agents and within less than a ten-year diagnosis. They were submitted to CGMS for 72h, whose data were compared with HbA1c and capillary glycemia. RESULTS: The average subcutaneous glucose excursion at breakfast was statistically bigger than at dinner (95 percentCI -24,96 a -1,66). The subcutaneous glucose excursion/meal carbohydrates content ratio was statistically bigger at breakfast than at other meals (p 0,001). There was no correlation between the levels of subcutaneous glucose and capillary glycemia with HbA1c. There weren’t complications using CGMS. CONCLUSIONS: The subcutaneous glucose excursions were predominant at breakfast. There were no correlations between HbA1c and glycemic control parameters. CGMS showed itself efficient, secure and well tolerated in this group of patients.


Subject(s)
Female , Humans , Male , Middle Aged , Blood Glucose Self-Monitoring/methods , Blood Glucose/analysis , /blood , Hyperglycemia/diagnosis , Postprandial Period , Blood Glucose Self-Monitoring/adverse effects , Chromatography, High Pressure Liquid , Glycated Hemoglobin/analysis , Prospective Studies , Reproducibility of Results
SELECTION OF CITATIONS
SEARCH DETAIL