ABSTRACT
An association between M. hominis and bacterial vaginosis (BV) was looked for in total 205 women characterized as having BV. Vaginal specimens from these patients were studied for the presence of amines, polymorphonuclear leukocytes, clue cells, and lactobacilli, and were also cultured to isolate Gardnerella vaginalis, M. hominis, Trichomonas vaginalis, Candida albicans and anaerobes. G. vaginalis was found to be the most common isolate from 132 cases (64.3%). M. hominis was isolated from 90 cases (43.9%). 62 per cent of M. hominis isolates were associated with G. vaginalis. 100 age matched control group revealed low prevalence of G. vaginalis and M. hominis whereas the difference in isolation rate of anaerobes was not significant. Anaerobes were found in association with M. hominis in 40 per cent cases. The treatment of these patients was decided after knowing the etiological agent.
Subject(s)
Adult , Bacteria, Anaerobic/isolation & purification , Doxycycline/therapeutic use , Female , Gardnerella vaginalis/isolation & purification , Humans , India , Metronidazole/therapeutic use , Mycoplasma/isolation & purification , Mycoplasma Infections/microbiology , Vaginosis, Bacterial/drug therapyABSTRACT
The incidence and prevalent biotypes of G. vaginalis in patients with non-specific vaginitis from Bombay, was studied. Of 300 patients screened, 105 were diagnosed to have nonspecific vaginitis (NSV). G. vaginalis was isolated from 71 per cent patients with NSV; 34.6 and 29.3 per cent G. vaginalis were belonging to biotypes 5 and 1 respectively. In 55 per cent patient, G. vaginalis was associated with anaerobes. None of the isolated strains of G. vaginalis was sensitive to 5 micrograms metronidazole disc whereas 93 per cent of the strains were sensitive to 50 micrograms metronidazole disc.