ABSTRACT
This article was aimed to explain the distribution of syndrome and study the change of pathogenesis in patients of acute exacerbation of chronic obstructive pulmonary disease risk-window (AECOPD-RW) based on clini-cal investigation. The data of the traditional Chinese medicine (TCM) syndrome of patients diagnosed as AECOPD into AECOPD-RW were collected from 8 hospitals. The database was established. Data was analyzed with SPSS 13.0 software. The results showed that among 15 basic syndromes, the syndrome of lung-qi deficiency was with the high-est frequency, which was followed by the syndrome of kidney-qi deficiency and syndrome of phlegm-dampness. A-mong 14 combined syndromes, the syndrome of lung-kidney qi deficiency and the syndrome of phlegm-dampness ac-cumulated in the lung were with the highest frequency. The common syndromes of AECOPD-RW were the syndrome of lung-kidney qi deficiency combined with the syndrome of phlegm-dampness accumulated in the lung, the syn-drome of lung-kidney qi deficiency, the syndrome of lung-spleen qi deficiency combined with the syndrome of phlegm-dampness accumulated in the lung, the syndrome of lung-spleen qi deficiency, the syndrome of lung-kidney qi-yin deficiency combined with the syndrome of phlegm-dampness accumulated in the lung, the syndrome of lung-kidney qi-yin deficiency, the syndrome of lung-kidney qi deficiency combined with the syndrome of phlegm-stasis accumulated in the lung, and the syndrome of lung-kidney qi-yin deficiency combined with the syndrome of phlegm-stasis accumulated in the lung. It was concluded that the main common syndromes of AECOPD-RW was the mixture of deficiency and excess. There was relatively less pure deficiency and excess syndrome.
ABSTRACT
This study was aimed to analyze the therapeutic effect of Shu-lung post with different stimula-tion intensities on chronic obstructive pulmonary disease (COPD), in order to determine the best stimulus intensity. A multicenter, randomized, controlled clinical trial was designed to take COPD patients at stable stage as study sub-jects. Patients were randomly divided into two groups, which were the foaming group and non-foaming group. The application was given 10 days before the summer dog days, on the 1st, 10th and 20th day within the dog days, and 10 days after the dog days. The results showed that a total of 164 cases were enrolled in the study, with 18 drop-out cases, and 146 cases fitted in the program. There was statistical difference on acute exacerbation frequency after treatment between the foaming group and non-foaming group (P < 0.05). There were statistical differences on clinical symptoms and signs of total score (P< 0.01) during the 8-month follow-up. It was concluded that Shu-lung post with different stimulation intensities were positively correlation with clinical efficacy.