ABSTRACT
Background: Yashada bhasma has been found to be very useful for the treatment of ailments like diabetes, eye disorder, urinary disorder etc. Since bhasma is a metallic preparation, so to prove its nontoxicity; modern standardization of the prepared samples is a must apart from other organoleptictests as mentioned in the ancient text.Objectives: The present study is aimed to synthesize bio-compatible Yashada bhasma from bioincompatible zinc metal. Further, comparative study of their chemical and physical properties throughsome quality control tests, physico-chemical tests and modern tests like XRD, DLS, Zeta potential, SEMand EDAX are carried out.Materials and methods: Yashada bhasma is prepared by a three step process i.e. Shodhan, Jarana andMarana. The inclusion of plant extracts and herbs during calcination process enhances its medicinalqualities, and reduces it to a nano size.Results: The XRD analysis of Yashada bhasma shows hexagonal ZnO crystalline phase whereas the rawmetal confirms the presence of crystallite Zinc metal. DLS shows reduction in particle size of YashadaBhasma (339.8 nm) as compared to raw metal (2063 nm) and this reduction is further supported by SEMwhich shows the particle size of Yashada bhasma (324 nm) and raw metal (1-2m). The zeta potential valueconfirms the stability of Yashada bhasma. EDAX revealed difference in concentration of Zinc and Oxygenin both the samples.Conclusion: An effort has been made to characterize the preparation of Yashada bhasma using sophisticated analytical tools as a step towards standardization of the bhasma. The results help in scientificallyestablishing the findings in line with the principle of Ayurveda.