ABSTRACT
Fahr's disease is a progressive and idiopathic basal ganglia calcification with normal metabolism of calcium and phosphor with motor and psychiatric signs and symptoms. Dementia, chorea athetosis, psychosis and depression due to Fahr's disease are frequently reported, but Fahr's disease with bipolar mood disorder manifestation is very rare and we found only 3 case in review of literature from 1955 to 2005.In this case report, a 21-year old girl is presented who was admitted to Sari-Zare psychiatric hospital for aggression, restlessness and insomnia. After mental status examination and Para clinical investigation, bipolar disorder due to Fahr's disease was detected. To date no specific treatment was found for this disease. This point is important that the patients with Fahr,s disease are sensitive to neuroleptic malignant syndrome