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Background: Hypertension may be the initial clinical presentation for at least 15 endocrine disorders, including overt and subclinical hyperthyroidism and hypothyroidism. The correction of thyroid dysfunction may normalize Blood Pressure (BP) in most cases, therefore checking thyroid function is essential during the workup for hypertension. The present study was conducted to find out the association between hypertension and thyroid dysfunction.Methods: It was a retrospective, observational study conducted among patients having hypertension visiting the outpatient department of Medicine in KIMS Karad, during the period of 2 months.Results: The mean values of various thyroid function parameters among hypertensive cases was assessed in the current study, Authors found that the mean Serum T3 level was 93.5917±32.82, Mean Serum T4 level was 6.72±1.64 and the mean Serum TSH level was 2.52±2.71. Among all the cases about 52% cases had deranged thyroid function reports.Conclusions: The results of this study suggest an association between subclinical hypothyroidism and increased blood pressure levels.
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Coronary artery disease (CAD) is the leading cause of mortality in men and women. Acute coronary syndrome (ACS), is a major reason for hospitalisation in our country. Dyslipidemia has been identified as one of the most important modifiable risk factors for CAD. The aim of the study was to determine the prevalence and pattern of dyslipidaemia and its relation to other modifiable risk factors.METHODS100 cases were studied in a Krishna Institutes of Medical Sciences, Karad, over a period of 12 months from 1st August 2015 to 31st July 2016. This is a prospective observational study. All adults >18 years of age admitted for acute coronary syndrome were eligible for this study. The ACS group was studied as STEMI, NSTEMI, and Unstable Angina.RESULTSMajority of patients (33) was in the age group 51-60 years followed by 29 patients in the age group 61-70 years. Out of 100 ACS patients, 62 were STEMI, 20 were NSTEMI, and 18 were unstable angina. The prevalence of ACS was higher in males than females. Hypertension is the most common risk factor of ACS (41%) followed by diabetes mellitus (33%). We found that high levels of TC (more than 200 mg/dl) were found in 31% patients [mean ± SD (167.79 mg/dl ± 45.28)]. High levels of LDL (more than 130 mg/dl) were found in 23% patients [mean ± SD (97.47 mg/dl ± 38.24)]. Low levels of HDL (less than 40 mg/dl) were found in 52% patients [mean ± SD (40.69 mg/dl ± 11.84)]. High levels of TG (more than 150 mg/dl) were found in 37 % patients [mean ± SD (145.28 mg/dl ± 65.78)].CONCLUSIONSDyslipidemia is one of the major risk factors which is widely prevalent in patients with ACS and is more prevalent in males than in females. We recommend paying more attention to serum lipids and other modifiable risk factors for prevention of ACS
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Introduction: A wide range of traditional and nontraditionalcardiovascular risk factors that may promote and fosterthe development of atherosclerosis have been reportedin association with the metabolic syndrome, includingatherogenic dyslipidemia, prothrombotic and proinflammatorymilieu, and endothelial dysfunction. The present study wasconducted to study the cardiovascular risk factors amongthe cases presented with metabolic syndrome in a tertiaryhealthcare institute.Material and methods: It was a cross sectional observationalstudy conducted among 100 cases diagnosed with metabolicsyndrome attending outpatient department of departmentof medicine, KIMS. Written consents were taken from theparticipants.Results: Mean Waist Circumference in cm was 99.62 ± 9.2,Hip Circumference was 106.3 ± 8.67 cm. The W/H ratiowas 0.93 ± 0.79. These indices were higher as compared tothe controls. 7.5 % cases had peripheral vascular disease,8.2% cases had coronary artery disease, 4% had nephroticsyndrome, 6% had history of cerebrovascular disease.Conclusions: Evaluation of the parameters in metabolicsyndrome can be a simple clinical tool to assess potentialrisk for development of cardiovascular diseases and henceassessment of prognosis and to establish and prioritize theresources appropriately.
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Introduction: Diabetes mellitus is a complex metabolicdisorder associated with an increased risk of microvascularand macrovascular disease. Type 2 diabetes mellitus is aprevalent metabolic disorder that often leads to cardiovasculardiseases and diabetic cardiomyopathy, which may lead tochronic pressure overload and myocardial infarction. Thepresent study aimed at studying the extent and complexity ofcardiovascular lesions among diabetic patients and comparesame with non-diabetic patients.Materials and methods: The present study was a CaseControl (Analytical and Interventional) Study conductedover 18 months (October 2016 to March 2018). Case groupconsisted of 250 Diabetic patients with cardiac symptoms,with or without ECG changes, who have undergone coronaryangiography. And Controls group consisted of 250 NonDiabetic patients with cardiac symptoms, with or withoutECG changes, have undergone coronary angiography.Results: In the present study, among diabetics, there were52.8% male patients and 47.2% female patients, similarlyamong non diabetic group, 57.2% were males and 42.8%cases were females. 12.4% people were found normal, 37.6%were suffering from Single vessel disease, 28.8% people withDouble vessel disease and 21.2% people with Triple vesseldisease.Conclusions: According to the present study, among coronaryangiography diagnosis, severe forms of coronary artery lesionswere found common among diabetic patients as compared tonon diabetic patients.