ABSTRACT
Introduction: Swelling of salivary glands, specifically parotid and submandibular gland presents as a common problem and being readily visible creates havoc among patients. In addition parotid/ submandibular swellings also remain a diagnostic challenge among clinicians. The aim of this study was to examine the sensitivity and specificity of Fine Needle Aspiration Cytology (FNAC) as a tool for diagnosis of salivary gland lesions. Materials and Methods: This prospective observational study was done for 6 months from January 2022 to June 2022 at Dhiraj General Hospital, SBKSMI and RC, Waghodia, Gujarat. In present study, total 42 cases were taken with salivary gland lesions that underwent FNAC in Pathology department. Results: In the present study, we had included 42 cases of salivary gland lesions. Out of 42cases, 12 (28.5%) cases were neoplastic and 30 (71.5%) cases were non-neoplastic. Among 12 neoplastic cases, 8 (67%) cases were found out to be benign and 4(33%) cases were diagnosed as malignant. Among malignant lesions, mucoepidermoid carcinoma has the highest number of cases (50%) followed by Carcinoma-ex pleomorphic adenoma and Adenoid cystic carcinoma. Conclusion: We found a good concordance between FNAC and final histology. Awareness of the therapeutic implications and limitations of the cytological interpretation amongst both the clinicians and the cytopathologists should enable FNAC to its best advantage.
ABSTRACT
Malignant peripheral nerve sheath tumor (MPNST) is derived from Schwann cells or pluripotent cells of the neural crest. MPNSTs (Malignant Peripheral Nerve Sheath Tumor) commonly arise in adult patients ranging from 20 to 50 years of age. They originate from a major or minor peripheral nerve branch or its sheath. The common sites of origin include the extremities and trunk. We reported a case of MPNST in 35 years old female patient with rapidly growing mass in her left thigh. Histopathological examination and immunohistochemistry confirmed the diagnosis of MPNST. This case report of Malignant peripheral nerve sheath tumor (MPNST) is presented because of its rarity.
ABSTRACT
Dysembryoplastic neuroepithelial tumor (DNET) is a rare benign tumor generally seen in children and adolescents with intractable epilepsy. This tumor demonstrates typical histological features such as glial nodules and the so called glioneuronal element. The diagnosis of DNET cannot rely just upon imaging features but needs a multidisciplinary contribution from the clinical and diagnostic department involving the clinician, radiologist as well as the pathologist to reach a definite and conclusive diagnosis. However histopathology is the gold standard for the final diagnosis.