Epidemiology And Patterns Of Isolated Limb Injuries At A Tertiary Care Hospital In Ahmedabad

INTRODUCTON: Due to recent advances in technologyan increasing number of peoplesuffer from trauma annuallywhich has resulted in change in fracture pattern.As there is a lack of recent systematic trauma registry in India, very little data is available to set up health care facilities.AIM: To determine epidemiology, pattern and initial outcome of patients admitted with isolated limb injury.METHOD: We conducted an observational study on isolated limb injuries without any musculoskeletal disorder at a tertiary care hospitalin Ahmedabad fromJune 2015 toMay2017. The limb injuries were classified as per the Limb Salvage Index score (LSI) for further management.RESULTS:we haveincluded 1300 patients inthis study. Mean age was 41.5 years and 68percent of them were males. Isolatedlimb injuries showed bi-modal age group with first peak between 21to 30 years and second at 41 to50 years. Road traffic accidents were the most common cause of injury followed by fall at home.The most commonly affected bone was femur in lower limb andradius intheupper limb.CONCLUSION: Ourstudy helped in identifying certain features that wouldbe useful for planning preventivestrategies, to reducethe numbers of accidents and redirect public investment in health.It also indicates establishment of trauma registry at local, state as well as national level.

Isolation of Mucilage from Cydonia vulgaris Pers. Seeds and its Evaluation as Superdisintegrant.

Gums and mucilages are preferably used as they are natural materials, for formulating conventional and novel dosage formulations. Natural materials have advantages over synthetic ones since they are chemically inert, nontoxic, less expensive, bio degradable and available in sufficient quantities. The study elaborates isolation of mucilage from the seeds of Cydonia vulgaris Pers. and explores it as tablet disintegrant. The mucilage was evaluated for all the parameters viz. solubility, swelling index, loss on drying, total ash, acid insoluble ash, microbial load and pH as per official monographs. The results confirmed that evaluation parameters were well within the limits. The disintegrating efficiency of isolated mucilage was equivalent to cross-povidone . The prepared batches were evaluated for hardness, friability, % drug content, wetting time, water absorption ratio and in vitro dispersion time. The results of isolated mucilage from Cydonia vulgaris Pers. were very promising.