ABSTRACT
Background: Aerobic bacteria are the major cause of pyogenic infections characterized by local and systemic inflammation and pus formation. Different studies show that bacterial profile of pus samples and their antimicrobial sensitivity pattern shows many variations. Emergence of antimicrobial drug resistance has made the treatment of pyogenic infections difficult. Pus culture and sensitivity testing done prior to start antibiotic therapy help in right approach towards selection of antibiotic and treatment. Methods: A study was conducted in Department of Microbiology of a private tertiary care hospital in Udaipur, Rajasthan from August 2017 to January 2018. Total of 240 pus samples were analyzed for aerobic culture and sensitivity. Processing and identification was done as per standard guidelines. Antibiotic sensitivity testing was performed by Kirby Baur disc diffusion method. Results: In our study, out of 240 pus samples sent from various departments, 160 (66.6%) were positive for bacterial growth. Commonest isolate was Staphylococcus aureus, followed by Pseudomonas species, E. coli, Klebsiella species, Enterococcus species, either alone or in mixed growth. All Staphylococcus aureus were sensitive to Vancomycin and Linezolid. For Pseudomonas species, effective drugs were piperacillin-tazobactem and polymyxin B; for enterobacteriacae, most effective drug was meropenem. Conclusion: It is of utmost importance for a clinician to send the pus sample for microbiological analysis and antibiotic sensitivity testing before starting antibiotic therapy to minimize the emergence of drug resistance.
ABSTRACT
Background: To understand the incidence amongst the age groups and gender, correlation of this study with the clinical presentation, evaluate the adequacy of ventilation by detecting blood gases, the changes in acid-base balance & compensatory mechanism in chronic obstructive pulmonary disease (COPD) patients, COPD cases were evaluated. Materials And Methods: The retrospective study was carried out on the patients with chronic obstructive pulmonary disease who were admitted in Civil hospital, Asarwa, Ahmedabad from July 2000 to October 2003. Arterial blood gas analysis was used as a diagnostic test in 50 cases of chronic obstructive pulmonary disease. Results: out of total 50 cases, majority (50%) had emphysema, 30% had mixed clinical picture of chronic bronchitis and emphysema, where as 20% had clinical picture of chronic bronchitis. Mean age group in this study was 55.9+4.4 yrs. Majority (82%) of patients were male. 16% cases were oedematous. Mean partial pressure of CO2 & O2 were 50.76 and 66.9 mm of Hg respectively. Range of pH observed was 7.28 to 7.52. Conclusion: Smoking of cigarettes (82%), exposure to dust (44%) and urban residence (64%) were the major risk factors.